通过离子液体氟化氢盐中的普林斯环化反应简便高效地合成含氟杂环化合物。
Facile and highly efficient synthesis of fluorinated heterocycles via Prins cyclization in ionic liquid hydrogen fluoride salts.
作者信息
Kishi Yuichiro, Nagura Hirokatsu, Inagi Shinsuke, Fuchigami Toshio
机构信息
Department of Electronic Chemistry, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, Japan.
出版信息
Chem Commun (Camb). 2008 Sep 7(33):3876-8. doi: 10.1039/b806389c. Epub 2008 Jun 24.
DOI:10.1039/b806389c
PMID:18726020
Abstract
Prins cyclization of homoallylic alcohols, thiols, and amines with various aldehydes in an ionic liquid HF salt (Et(4)NF.5HF) afforded the corresponding 4-fluorinated heterocycles in excellent yields.
摘要
在离子液体HF盐（Et(4)NF·5HF）中，烯丙醇、硫醇和胺与各种醛进行普林斯环化反应，以优异的产率得到相应的4-氟代杂环化合物。
Zotero 插件