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儿童门诊牙科手术两种全身麻醉方式的恢复质量:一项双盲随机试验

Quality of recovery from two types of general anesthesia for ambulatory dental surgery in children: a double-blind, randomized trial.

作者信息

König Matthias W, Varughese Anna M, Brennen Kathleen A, Barclay Sean, Shackleford T Michael, Samuels Paul J, Gorman Kristin, Ellis Jillian, Wang Yu, Nick Todd G

机构信息

Department of Anesthesiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

出版信息

Paediatr Anaesth. 2009 Aug;19(8):748-55. doi: 10.1111/j.1460-9592.2009.03054.x. Epub 2009 Jun 15.

Abstract

BACKGROUND

Pediatric dental procedures are increasingly performed under general anesthesia because of the inability to cooperate, situational anxiety, or other behavioral problems. Volatile anesthetics have been associated with emergence delirium in children, whereas the use of propofol for anesthetic maintenance has been shown to reduce the incidence of emergence delirium after other types of surgeries. The aim of this study is to compare a sevoflurane-based anesthetic with a propofol-based technique as it relates to the incidence of emergence delirium and the quality of recovery after pediatric dental surgery, in patients who present with risk factors for perioperative behavioral issues.

METHODS

We prospectively collected data of 179 pediatric patients scheduled for ambulatory dental surgery using a double-blind and randomized trial design. Subjects were anesthetized following standardized protocols for either a sevoflurane- or a propofol-based technique. The incidence of emergency delirium, as measured by the Pediatric Anesthesia Emergence Delirium score, was the primary outcome. Secondary outcomes included the incidence of postoperative nausea and vomiting (PONV), number of nursing interventions in the recovery room, time to discharge readiness, and parental satisfaction.

RESULTS

We found no difference in the incidence of emergence delirium after both types of anesthesia. However, use of sevoflurane significantly increased both the risk of PONV and the number of postoperative nursing interventions. Discharge criteria were met about 10 min earlier in patients anesthetized with sevoflurane. Parental satisfaction was equally high with both anesthesia regimens.

CONCLUSIONS

A propofol-based anesthetic technique did not lead to a lower incidence of emergence delirium after dental surgery in children but did result in significantly less PONV and fewer postoperative nursing interventions.

摘要

背景

由于儿童无法配合、情境性焦虑或其他行为问题,儿科牙科手术越来越多地在全身麻醉下进行。挥发性麻醉剂与儿童苏醒期谵妄有关,而在其他类型手术中,使用丙泊酚维持麻醉已被证明可降低苏醒期谵妄的发生率。本研究的目的是比较七氟醚麻醉与丙泊酚麻醉技术,探讨其与儿科牙科手术后苏醒期谵妄发生率及恢复质量的关系,研究对象为存在围手术期行为问题风险因素的患者。

方法

我们采用双盲随机试验设计,前瞻性收集了179例计划进行门诊牙科手术的儿科患者的数据。受试者按照标准化方案接受七氟醚或丙泊酚麻醉技术麻醉。以小儿麻醉苏醒期谵妄评分衡量的苏醒期谵妄发生率为主要观察指标。次要观察指标包括术后恶心呕吐(PONV)发生率、恢复室护理干预次数、出院准备时间及家长满意度。

结果

我们发现两种麻醉方式后苏醒期谵妄的发生率没有差异。然而,使用七氟醚显著增加了PONV风险和术后护理干预次数。使用七氟醚麻醉的患者达到出院标准的时间早约10分钟。两种麻醉方案的家长满意度同样高。

结论

丙泊酚麻醉技术在儿童牙科手术后并未降低苏醒期谵妄的发生率,但确实显著减少了PONV和术后护理干预次数。

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