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自我报告的农村糖尿病患者糖尿病视网膜病变的危险因素。

Risk factors for diabetic retinopathy in self-reported rural population with diabetes.

作者信息

Rani P K, Raman R, Chandrakantan A, Pal S S, Perumal G M, Sharma T

机构信息

Vision Research Foundation, Sankara Nethralaya Diabetic Retinopathy Project, 18, College Road, Sankara Nethralaya, Chennai - 600 006, Tamil Nadu,

出版信息

J Postgrad Med. 2009 Apr-Jun;55(2):92-6. doi: 10.4103/0022-3859.48787.

Abstract

BACKGROUND

Diabetes and its related microvascular complications like diabetic retinopathy (DR) are showing increased prevalence in India. However, the magnitude of DR in rural population with diabetes needs exploration.

AIM

To estimate the prevalence and risk factors for the presence and severity of diabetic retinopathy in the self-reported rural population with diabetes.

SETTINGS AND DESIGN

In a cross-sectional study, a total of 26,519 participants (age >or= 30 years) attended 198 diabetic retinopathy screening camps conducted in three southern districts of Tamilnadu, India, between February 2004 and April 2006.

MATERIALS AND METHODS

All the participants underwent a dilated eye examination to detect DR by indirect ophthalmoscopy. Systemic and ocular risk factor estimation was done in a comprehensive examination.

STATISTICAL ANALYSIS

Univariate and stepwise regression analyses were done to identify the independent risk factors associated with the presence and severity of retinopathy.

RESULTS

The prevalence of diabetic retinopathy was 17.6% among the self-reported rural population with diabetes. The prevalence of referable (sight threatening) retinopathy was 5.3%. Risk factors associated with the development of any DR were male gender (OR= 1.37), longer duration of diabetes (per year, OR= 1.07), lean body mass index (OR= 1.30), higher systolic blood pressure (per 10 mm Hg, OR= 1.18), and insulin treatment (OR= 1.34; P P CONCLUSION: The study identified risk factors associated with DR in the rural population with diabetes. The results suggested that there was a need for formulating effective preventive strategies to minimize avoidable blindness due to diabetes, in rural areas.

摘要

背景

糖尿病及其相关微血管并发症如糖尿病视网膜病变(DR)在印度的患病率呈上升趋势。然而,糖尿病农村人口中DR的严重程度有待探究。

目的

估计自我报告的农村糖尿病患者中糖尿病视网膜病变的患病率及其存在和严重程度的危险因素。

设置与设计

在一项横断面研究中,2004年2月至2006年4月期间,共有26519名年龄≥30岁的参与者参加了在印度泰米尔纳德邦三个南部地区举办的198场糖尿病视网膜病变筛查营。

材料与方法

所有参与者均接受散瞳眼部检查,通过间接检眼镜检测DR。在全面检查中进行全身和眼部危险因素评估。

统计分析

进行单因素和逐步回归分析,以确定与视网膜病变的存在和严重程度相关的独立危险因素。

结果

在自我报告的农村糖尿病患者中,糖尿病视网膜病变的患病率为17.6%。可转诊(威胁视力)视网膜病变的患病率为5.3%。与任何DR发生相关的危险因素包括男性(OR = 1.37)、糖尿病病程较长(每年,OR = 1.07)、瘦体重指数(OR = 1.30)、收缩压较高(每10 mmHg,OR = 1.18)以及胰岛素治疗(OR = 1.34;P P结论:该研究确定了农村糖尿病患者中与DR相关的危险因素。结果表明,有必要制定有效的预防策略,以尽量减少农村地区因糖尿病导致的可避免失明。

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