三种丹皮酚席夫碱锌（II）配合物的合成、荧光研究及生物学评价
Synthesis, fluorescence study and biological evaluation of three Zn(II) complexes with Paeonol Schiff base.
作者信息
Qin Dong-dong, Yang Zheng-yin, Qi Gao-fei
机构信息
College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China.
出版信息
Spectrochim Acta A Mol Biomol Spectrosc. 2009 Oct 1;74(2):415-20. doi: 10.1016/j.saa.2009.06.037. Epub 2009 Jun 21.
The synthesis of three Paeonol Schiff base ligand and their Zn(II) complexes are reported. The complexes were fully characterized by IR, (1)H NMR, elemental analysis and molar conductivity. The experiment results show the three Zn(II) complexes can emit bright fluorescence at room temperature in DMF solution and solid state. The fluorescence quantum yields (Phi) of three Schiff base ligands and their Zn(II) complexes were calculated using quinine sulfate as the reference with a known Phi(R) of 0.546 in 1.0N sulfuric acid. Furthermore, in order to develop these Zn(II) complexes' biological value, the antioxidant activities against hydroxyl radicals (OH*) were evaluated. The results show the three complexes possess excellent ability to scavenge hydroxyl radicals.
报道了三种丹皮酚席夫碱配体及其锌（II）配合物的合成。通过红外光谱、核磁共振氢谱、元素分析和摩尔电导率对配合物进行了全面表征。实验结果表明，三种锌（II）配合物在室温下于二甲基甲酰胺溶液和固态中均可发出明亮的荧光。以硫酸奎宁为参比，在1.0N硫酸中其荧光量子产率（Phi）已知为0.546，计算了三种席夫碱配体及其锌（II）配合物的荧光量子产率。此外，为了开发这些锌（II）配合物的生物学价值，评估了它们对羟基自由基（OH*）的抗氧化活性。结果表明，这三种配合物具有优异的清除羟基自由基的能力。
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