Manchikanti Laxmaiah, Singh Vijay, Helm Standiford, Schultz David M, Datta Sukdeb, Hirsch Joshua A
Pain Management Center of Paducah, Paducah, KY, USA.
Pain Physician. 2009 Jul-Aug;12(4):E1-33.
Practice guidelines are systematically developed statements to assist practitioners and patients in making decisions about appropriate health care for specific clinical circumstances. Clinical practice guidelines present statements of best practice based on a thorough evaluation of the evidence from published studies on the outcomes of treatment. In November 1989, Congress mandated the creation of the Agency for Healthcare Policy and Research (AHCPR). AHCPR was given broad responsibility for supporting research, data development, and related activities. Associated with this mandate, the National Academy of Sciences published a document indicating that guidelines are expected to enhance the quality, appropriateness, and effectiveness of health care services. Guidelines as a whole have been characterized by multiple conflicts in terminology and technique. These conflicts are notable for the confusion they create and for what they reflect about differences in values, experiences, and interest among different parties. Despite this confusion, public and private development of guidelines is growing exponentially. There are only limited means to coordinate these guidelines in order to resolve inconsistencies, fill in gaps, track applications and results, and assess the soundness of individual guidelines. Significant diversity exists in clinical practice guidelines. The inconsistency amongst guidelines arises from variations in values, tolerance for risks, preferences, expertise, and conflicts of interest. In 2000, the American Society of Interventional Pain Physicians (ASIPP) first created treatment guidelines to help practitioners. There have been 4 subsequent updates. These guidelines address the issues of systematic evaluation and ongoing care of chronic or persistent pain, and provide information about the scientific basis of recommended procedures. These guidelines are expected to increase patient compliance, dispel misconceptions among providers and patients, manage patient expectations reasonably, and form the basis of a therapeutic partnership between the patient, the provider, and payors. The ASIPP guidelines are based on evidence-based medicine (EBM). EBM is in turn based on 4 basic contingencies: the recognition of the patient's problem and the construction of a structured clinical question; the ability to efficiently and effectively search the medical literature to retrieve the best available evidence to answer the clinical question; clinical appraisal of the evidence; and integration of the evidence with all aspects of the individual patient's decision-making to determine the best clinical care of the patient. Evidence synthesis for guidelines includes the review of all relevant systematic reviews and individual articles, grading them for relevance, methodologic quality, consistency, and recommendations.
实践指南是系统制定的声明,旨在协助从业者和患者针对特定临床情况做出有关适当医疗保健的决策。临床实践指南基于对已发表的治疗结果研究证据的全面评估,呈现最佳实践声明。1989年11月,国会授权成立医疗保健政策与研究机构(AHCPR)。AHCPR被赋予支持研究、数据开发及相关活动的广泛职责。与此授权相关,美国国家科学院发布了一份文件,表明指南有望提高医疗保健服务的质量、适当性和有效性。总体而言,指南在术语和技术方面存在多重冲突。这些冲突因其造成的混乱以及它们所反映的不同各方在价值观、经验和利益方面的差异而值得关注。尽管存在这种混乱,但指南的公共和私人制定正在呈指数级增长。协调这些指南以解决不一致之处、填补空白、跟踪应用和结果以及评估个别指南的合理性的手段有限。临床实践指南存在显著差异。指南之间的不一致源于价值观、风险承受能力、偏好、专业知识和利益冲突的差异。2000年,美国介入性疼痛医师协会(ASIPP)首次制定治疗指南以帮助从业者。随后进行了4次更新。这些指南涉及慢性或持续性疼痛的系统评估和持续护理问题,并提供有关推荐程序科学依据的信息。这些指南有望提高患者的依从性,消除提供者和患者之间的误解,合理管理患者期望,并构成患者、提供者和支付方之间治疗伙伴关系的基础。ASIPP指南基于循证医学(EBM)。循证医学又基于4个基本条件:识别患者问题并构建结构化临床问题;高效有效地检索医学文献以获取最佳可用证据来回答临床问题的能力;对证据的临床评估;以及将证据与个体患者决策的各个方面相结合以确定患者的最佳临床护理。指南的证据综合包括对所有相关系统评价和个别文章的审查,根据相关性、方法学质量、一致性和建议对它们进行分级。