快速抗原检测对甲型流感大流行（H1N1）2009 病毒的临床敏感性差。
Poor clinical sensitivity of rapid antigen test for influenza A pandemic (H1N1) 2009 virus.
机构信息
Institute of Virology, Bonn, Germany.
出版信息
Emerg Infect Dis. 2009 Oct;15(10):1662-4. doi: 10.3201/eid1510.091186.
Abstract
Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.
摘要
德国波恩的 144 份临床样本通过逆转录-PCR 检测到了甲型 H1N1 流感大流行病毒 RNA。在这些样本中，常用的快速抗原检测法仅检测出 11.1%的病毒。快速检测阳性样本的主要特征是高病毒浓度。在当前的大流行中，基于抗原的快速检测似乎不适合用于病毒学诊断。
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