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用于产生医学相关的铥-167的质子诱发(167)铒核反应激发函数的实验研究

Experimental study of the excitation functions of proton induced nuclear reactions on (167)Er for production of medically relevant (167)Tm.

作者信息

Tárkányi F, Hermanne A, Takács S, Király B, Spahn I, Ignatyuk A V

机构信息

Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), 4026 Debrecen, Bem ter 18/c, Hungary.

出版信息

Appl Radiat Isot. 2010 Feb;68(2):250-5. doi: 10.1016/j.apradiso.2009.10.043. Epub 2009 Oct 28.

Abstract

(167)Tm (T(1/2)=9.25d) is a candidate radioisotope for medical therapy and diagnostics due to its Auger-electron and low-energy X- and gamma-ray emission. Excitation functions of the (167)Er(p,n)(167)Tm reaction and (168)Er(p,n)(168)Tm, (167)Er(p,2n)(166)Tm, (166)Er(p,2n)(165)Tm disturbing reactions were measured up to 15MeV by using the stacked foil irradiation technique and gamma-ray spectroscopy. The measured excitation functions agree well with the results of ALICE-IPPE, EMPIRE-II and TALYS nuclear reaction model codes. The thick target yield of (167)Tm in the 15-8MeV energy range is 6.9MBq/microAh. A short comparison of charged particle production routes of (167)Tm is given.

摘要

(167)Tm(半衰期T(1/2)=9.25天)因其俄歇电子以及低能X射线和γ射线发射,是一种用于医学治疗和诊断的候选放射性同位素。利用叠层箔辐照技术和γ射线能谱,测量了(167)Er(p,n)(167)Tm反应以及(168)Er(p,n)(168)Tm、(167)Er(p,2n)(166)Tm、(166)Er(p,2n)(165)Tm干扰反应的激发函数,测量范围高达15MeV。测量得到的激发函数与ALICE - IPPE、EMPIRE - II和TALYS核反应模型代码的结果吻合良好。(167)Tm在15 - 8MeV能量范围内的厚靶产额为6.9MBq/μAh。给出了(167)Tm带电粒子产生途径的简要比较。

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