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体重指数、年龄和性别对现患疾病的影响:一项横断面研究。

The influence of body mass index, age and gender on current illness: a cross-sectional study.

机构信息

Department of Psychology, Brigham Young University, Provo, UT 84604, USA.

出版信息

Int J Obes (Lond). 2010 Mar;34(3):429-36. doi: 10.1038/ijo.2009.258. Epub 2009 Dec 15.

Abstract

CONTEXT

Obesity poses a significant health risk, but health risk is not equivalent to actual health status. Further, age and gender might alter the effect of body weight on physical health.

OBJECTIVE

To determine the relationship between body mass index (BMI), age, gender and current health status.

DESIGN

Data from the 1988-1994, 2003-2004 and 2005-2006 National Health & Nutrition Examination Surveys were weighted to represent the US population. BMI, age, gender and current medication use were analyzed in a sample-adjusted 9071 women and 8880 men.

MAIN OUTCOME MEASURES

The percentage of participants taking medication and the total number of medications taken.

RESULTS

In both the 1988-1994 and 2003-2006 data sets, with few exceptions, medication loads did not increase significantly in overweight compared with normal-weight people. Medication loads increased significantly in obese compared with normal-weight people aged 40+, but only marginally at 25-39 years. Medication loads were higher in women than men, but significantly less so in people aged 55-70.

CONCLUSIONS

First, medication loads, a measure of current health status, were increased in obese compared with the normal-weight people, but the effect was mainly at ages over 40 years. In addition, BMI category contributed less to medication loads at ages 25-39 than in older groups. Second, there was little difference in current health status in normal-weight versus overweight people at all ages. Finally, higher medication loads in women than men are more apparent in younger than older people. Although obesity does not substantially affect current health in young people, it is likely that the increased medication loads in obese compared with normal-weight older people originates at least in part from an increased BMI starting at a younger age. Thus, age, gender and onset of high BMI all require consideration when using BMI to assess current health status.

摘要

背景

肥胖对健康构成重大风险,但健康风险并不等同于实际健康状况。此外,年龄和性别可能会改变体重对身体健康的影响。

目的

确定体重指数(BMI)、年龄、性别与当前健康状况之间的关系。

设计

对 1988-1994 年、2003-2004 年和 2005-2006 年全国健康与营养调查的数据进行加权处理,以代表美国人口。在调整样本后的 9071 名女性和 8880 名男性中分析 BMI、年龄、性别和当前用药情况。

主要观察指标

服用药物的参与者比例和服用药物的总数。

结果

在 1988-1994 年和 2003-2006 年的数据集中,除少数例外情况外,与正常体重者相比,超重者的药物负荷并没有显著增加。与正常体重者相比,40 岁以上肥胖者的药物负荷显著增加,但在 25-39 岁时略有增加。女性的药物负荷高于男性,但在 55-70 岁人群中差异显著较小。

结论

第一,药物负荷是当前健康状况的衡量标准,与正常体重者相比,肥胖者的药物负荷增加,但这种影响主要发生在 40 岁以上人群中。此外,与较年长人群相比,25-39 岁人群的 BMI 类别对药物负荷的影响较小。第二,在所有年龄段,正常体重者与超重者的当前健康状况差异不大。最后,与较年长人群相比,年轻人群中女性的药物负荷高于男性更为明显。尽管肥胖对年轻人的当前健康状况没有实质性影响,但与正常体重者相比,肥胖者药物负荷增加的原因可能至少部分源于年轻时 BMI 的增加。因此,在使用 BMI 评估当前健康状况时,年龄、性别和 BMI 起始时间都需要考虑。

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