Sepahi Mohsen Akhavan, Heidari Akram, Shajari Ahmad
Department of Pediatric Nephrology, Clinical Research Development Center, Iran.
Saudi J Kidney Dis Transpl. 2010 Jan;21(1):181-4.
Urolithiasis is one of the commonest problems in pediatric nephrology. Prevalence of urolithiasis in pediatric patients is increasing. The purpose was to properly diagnose and treat with the special attention to the risk factors. This study is case-series and was performed on 100 pediatric patients for evaluation of clinical manifestation and etiology of renal stone in Qom. Hundred Children, fewer than 14 years old with mean age of 3.32 years, were included (54% male). Etiology of urolithiasis in 5% was unclear. Metabolic disorders found in patients were mainly: Hypocitraturia in 54, hyperoxaluria in 14, hyperuricosuria in 25, cystinuria in 6, hypercalciuria in 28 and phosphaturia in 8 patients. The main clinical presentation was fever, pain, irritability, dysuria and hematuria. Family history of urolithiasis was found in 23% of patients and 54% presented with urinary tract infection (UTI). We conclude that majority of patients were symptomatic and hypocitraturia was the commenest risk factor among others.
尿路结石是小儿肾脏病最常见的问题之一。小儿患者尿路结石的患病率正在上升。目的是进行正确诊断和治疗,并特别关注危险因素。本研究为病例系列研究,对100例小儿患者进行了研究,以评估库姆地区肾结石的临床表现和病因。纳入了100名14岁以下儿童,平均年龄3.32岁(54%为男性)。5%的尿路结石病因不明。患者中发现的代谢紊乱主要有:54例低枸橼酸尿症、14例高草酸尿症、25例高尿酸尿症、6例胱氨酸尿症、28例高钙尿症和8例磷酸盐尿症。主要临床表现为发热、疼痛、烦躁、排尿困难和血尿。23%的患者有尿路结石家族史,54%的患者有尿路感染(UTI)。我们得出结论,大多数患者有症状,低枸橼酸尿症是最常见的危险因素。