European Organization for Research and Treatment of Cancer, Elderly Task Force, EORTC Headquarters, Avenue E. Mounierlaan, 83/11, B-1200 Brussels, Belgium.
Eur J Cancer. 2010 Apr;46(6):1019-25. doi: 10.1016/j.ejca.2010.01.006.
Due to the ageing of the population in the Western world, a significant increase in the number of older patients diagnosed with neoplastic diseases is observed. Hence, there is an emerging need for tools to efficiently evaluate older patients' functional and global status. These tools can allow treating oncologists to better select patients, to propose treatment modifications, implement supportive measures and develop interventions to decrease the risk of toxicity and in general better tailor the treatment plan on an individual level. Currently significant uncertainty exists about the optimal tools and strategy for geriatric assessment, but on the other hand there is more than enough evidence that (some form of) geriatric assessment detects many previously unrecognised problems, and allows directed intervention which can improve outcome and compliance of proposed treatments. In the present paper, we discuss the most commonly used and studied tools for the assessment of functional status of older cancer patients.
由于西方世界人口老龄化,被诊断患有肿瘤性疾病的老年患者数量显著增加。因此,需要开发有效的工具来评估老年患者的功能和整体状态。这些工具可以帮助肿瘤学家更好地选择患者,提出治疗修改建议,实施支持性措施,制定干预措施来降低毒性风险,并且能够更好地根据个体情况制定治疗计划。目前,关于老年评估的最佳工具和策略存在很大的不确定性,但另一方面,有足够的证据表明(某种形式的)老年评估可以发现许多以前未被识别的问题,并进行有针对性的干预,从而改善治疗方案的效果和依从性。在本文中,我们将讨论最常用于评估老年癌症患者功能状态的工具。