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水蛭疗法在皮肤外科手术及疾病中的应用

Leech therapy in cutaneous surgery and disease.

作者信息

Mamelak Adam J, Jackson Adrianna, Nizamani Rabia, Arnon Ofer, Liegeois Nanette J, Redett Richard J, Byrne Patrick J

机构信息

Department of Dermatology, The Methodist Hospital, Houston, TX , USA.

出版信息

J Drugs Dermatol. 2010 Mar;9(3):252-7.

Abstract

BACKGROUND

Over the ages, the use of leeches in medicine has evolved from haphazard bloodletting to a well-understood physiologic process with defined, rational applications.

OBJECTIVE

The authors describe the current role of leech therapy in cutaneous surgery and medicine.

METHODS

Case series and review of the literature.

RESULTS

Leech saliva contains anticoagulative, anti-aggregative and vasodilatory components. Combined with the annelid's mechanical ability to extract blood, leeches can contribute to patients' health with minimal risks.

CONCLUSION

Leeches should be considered as novel therapies for disorders of coagulation and venous congestion. Implementation of leech treatment should be tempered with the potential adverse effects, including Aeromonas infection and a drop in hematocrit that might require a blood transfusion.

摘要

背景

长期以来,水蛭在医学中的应用已从随意的放血发展为一个得到充分理解的生理过程,具有明确、合理的应用方式。

目的

作者描述了水蛭疗法在皮肤外科和医学中的当前作用。

方法

病例系列和文献综述。

结果

水蛭唾液含有抗凝、抗聚集和血管舒张成分。结合环节动物提取血液的机械能力,水蛭可以以最小的风险促进患者健康。

结论

水蛭应被视为治疗凝血和静脉充血障碍的新型疗法。水蛭治疗的实施应考虑到潜在的不良反应,包括气单胞菌感染和血细胞比容下降,后者可能需要输血。

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