Institute of Internal Medicine, Angiology and Arteriosclerosis, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Rheumatol Int. 2012 May;32(5):1367-70. doi: 10.1007/s00296-010-1404-7. Epub 2010 Mar 18.
A 62-year-old man presented with a 2-month history of increasing pain in the left hip. Magnetic resonance imaging (MRI) showed bone marrow edema (BME) of the left femur, dual energy X-ray absorptiometry (DXA) showed osteopenia at the same level, whereas pelvis X-rays failed to show any objective findings. After ruling out other possible causes of BME such as aseptic osteonecrosis, infectious arthritis, primary or metastatic malignancy, tuberculosis, osteomyelitis, rheumatoid arthritis, and seronegative spondyloarthropathies, a diagnosis of transient osteoporosis of the hip (TOH) was made, and treatment with teriparatide at a daily dose of 20 μg was started and continued for 4 weeks. Disappearance of the symptoms and normalization of MRI were obtained.
一位 62 岁男性因左髋部疼痛加剧就诊,病史为 2 个月。磁共振成像(MRI)显示左股骨骨髓水肿(BME),双能 X 射线吸收法(DXA)显示同一水平骨质疏松,而骨盆 X 射线未显示任何客观发现。排除了其他可能导致 BME 的原因,如无菌性骨坏死、感染性关节炎、原发性或转移性恶性肿瘤、结核、骨髓炎、类风湿关节炎和血清阴性脊柱关节病后,诊断为髋部一过性骨质疏松症(TOH),开始每日 20 μg 特立帕肽治疗,持续 4 周。症状消失,MRI 恢复正常。