University Department of Dermatology and Venereology, Zagreb University Hospital Centre and Zagreb University School of Medicine, Salata 4, 10000 Zagreb, Croatia.
Clin Dermatol. 2010 Mar 4;28(2):146-50. doi: 10.1016/j.clindermatol.2009.12.007.
Significant changes in epidemiology, etiology, and the clinical pattern of mycotic infections caused by Microsporum spp have been observed in recent years. Fungal infections caused by M canis, followed by M gypseum and M hominis, involving skin and its appendages, represent one of the most common diseases worldwide and a recalcitrant problem in dermatology that demands appropriate diagnostic and treatment strategies. The most striking clinical phenomena of superficial and kerion and other forms of tinea, such as tinea capitis, fungal infections of the glabrous skin (tinea pedis, manus, cruris et corporis), and even onychomycosis due to Microsporum spp are described, with emphasis on the changes that have occurred in the last decade. The data on significant differences in the prevalence and clinical pattern of the fungal skin infections caused by Microsporum spp today compared with the data at the beginning of the epidemic breakout might still be rather controversial, depending also on the patients' lifestyle and geography. In general, physicians should be aware of the clinical spectrum of mycotic infections due to Microsporum spp to avoid mistakes in identifying the fungal etiology and to provide patients with the proper therapy.
近年来,由小孢子菌属引起的真菌病的流行病学、病因学和临床模式发生了重大变化。由犬小孢子菌引起的真菌感染,其次是石膏小孢子菌和厚皮马拉色菌,累及皮肤及其附属器,是全球最常见的疾病之一,也是皮肤科的一个顽疾,需要采取适当的诊断和治疗策略。本文描述了小孢子菌属引起的浅部和脓癣等其他形式的癣病(如头癣)、无毛发皮肤(足癣、手癣、股癣和体癣)以及甚至甲癣的最显著的临床现象,并重点介绍了过去十年中发生的变化。目前,与疫情爆发初期相比,小孢子菌属引起的真菌性皮肤感染的流行率和临床模式存在显著差异,这一数据可能仍存在争议,这也取决于患者的生活方式和地理位置。一般来说,医生应该了解由小孢子菌属引起的真菌病的临床谱,以避免在确定真菌病因时出错,并为患者提供适当的治疗。