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建立儿童龋病风险评估模型。

Building caries risk assessment models for children.

机构信息

Dental Public Health, Faculty of Dentistry, University of Hong Kong.

出版信息

J Dent Res. 2010 Jun;89(6):637-43. doi: 10.1177/0022034510364489. Epub 2010 Apr 16.

Abstract

UNLABELLED

Despite the well-recognized importance of caries risk assessment, practical models remain to be established. This study was designed to develop biopsychosocial models for caries risk assessment in various settings. With a questionnaire, an oral examination, and biological (salivary, microbiological, and plaque pH) tests, a prospective study was conducted among 1782 children aged 3-6 years, with 1576 (88.4%) participants followed in 12 months. Multiple risk factors, indicators, and protective factors were identified. Various risk assessment models were constructed by the random selection of 50% of the cases and further validated in the remaining cases. For the prediction of a "one-year caries increment", screening models without biological tests achieved a sensitivity/specificity of 82%/73%; with biological tests, full-blown models achieved the sensitivity/specificity of 90%/90%. For identification of a quarter of the children with high caries burden (baseline dmft > 2), a community-screening model requiring only a questionnaire reached a sensitivity/specificity of 82%/81%. These models are promising tools for cost-effective caries control and evidence-based treatment planning.

ABBREVIATIONS

decayed, missing, filled teeth in primary dentition (dmft); receiver operation characteristics (ROC); relative risk (RR); confidence interval (CI); National Institutes of Health (NIH); World Health Organization (WHO); US Department of Health and Human Services (US/DHHS); American Academy of Pediatric Dentistry (AAPD).

摘要

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尽管龋病风险评估的重要性已得到广泛认可,但仍需要建立实用的模型。本研究旨在为不同环境下的龋病风险评估制定生物心理社会模型。通过问卷调查、口腔检查和生物(唾液、微生物学和菌斑 pH 值)测试,对 1782 名 3-6 岁儿童进行了前瞻性研究,其中 1576 名(88.4%)参与者在 12 个月内得到了随访。确定了多种风险因素、指标和保护因素。通过随机选择 50%的病例构建了各种风险评估模型,并在其余病例中进一步验证了这些模型。对于预测“一年龋齿增量”,不包括生物测试的筛选模型的灵敏度/特异性为 82%/73%;包括生物测试的全面模型的灵敏度/特异性为 90%/90%。为了确定四分之一具有高龋齿负担(基线 dmft>2)的儿童,仅需要问卷调查的社区筛查模型达到了 82%/81%的灵敏度/特异性。这些模型是具有成本效益的龋齿控制和基于证据的治疗计划的有前途的工具。

缩写

乳牙龋失补牙面数(dmft);受试者工作特征(ROC);相对风险(RR);置信区间(CI);美国国立卫生研究院(NIH);世界卫生组织(WHO);美国卫生与公众服务部(US/DHHS);美国儿科学会牙科分会(AAPD)。

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