St. Luke's-Roosevelt Hospital Center Behavioral Science Research Unit, 11th Fl., 1111 Amsterdam Ave., New York, NY 10025, USA.
Psychosomatics. 2010 May-Jun;51(3):257-66. doi: 10.1176/appi.psy.51.3.257.
"Nonmedical" (i.e., illicit) use of opioid analgesics has skyrocketed among the general population during the past decade, with similar increases observed among pain patients who take opioids by prescription.
Because 1 in 3 opioid-maintained pain patients may be affected, it is essential that healthcare providers learn more about this subpopulation as a first step toward improved detection, brief intervention, referral, and general management.
The authors examined baseline data for 40 chronic-pain patients in a treatment trial targeting opioid analgesic abuse.
Abuse-disorder patients were dysfunctional and had high rates of psychiatric disorders and troublesome personality traits. Providers characterized patients as manipulative, drug-seeking, and noncompliant; patients complained that they were pharmacologically undertreated and were considered "addicts." Despite having severe pain and addiction, their average daily opioid dose was only 69% of that used to treat addiction in the same geographic region.
Abuse-disorder patients had a similar physical but worse psychiatric/personality presentation than other chronic-pain patients, which suggests the need for increased psychiatric involvement.
在过去十年中,普通人群中“非医疗”(即非法)使用阿片类镇痛药的情况急剧上升,而按处方服用阿片类药物的疼痛患者也出现了类似的增长。
由于每 3 名接受阿片类药物维持治疗的疼痛患者中就有 1 名可能受到影响,因此医护人员必须更多地了解这一亚群,这是提高发现率、进行简短干预、转介和一般管理的第一步。
作者检查了针对阿片类药物滥用治疗试验中的 40 名慢性疼痛患者的基线数据。
滥用障碍患者功能失调,精神障碍和不良人格特征的发生率较高。医护人员将患者描述为善于操纵、觅药和不遵守规定;患者抱怨他们的药物治疗不足,并被认为是“瘾君子”。尽管他们有严重的疼痛和成瘾,但他们的平均日阿片类药物剂量仅为同一地理区域治疗成瘾所用剂量的 69%。
与其他慢性疼痛患者相比,滥用障碍患者的身体状况相似,但精神/人格状况更差,这表明需要更多的精神科参与。