Department of Urology, New York University Langone Medical Center, New York University Cancer Institute, New York, NY 10016, USA.
Urol Oncol. 2010 Sep-Oct;28(5):568-74. doi: 10.1016/j.urolonc.2010.03.018.
The surgical management of kidney tumors has significantly evolved over the past decade. Partial nephrectomy and nephron sparing surgery have emerged as the treatments of choice for most newly diagnosed kidney tumors at tertiary care centers. The trend towards an organ sparing approach is largely due to an improved understanding of the global importance of kidney function as well as the impact that kidney surgery may have on non-oncologic morbidity and mortality. In addition to reviewing the methods of evaluating kidney function, this article discusses the effectiveness of various nephron sparing techniques in preserving kidney function and improving non-oncologic outcomes.
过去十年中,肾脏肿瘤的外科治疗取得了显著进展。部分肾切除术和保留肾单位手术已成为三级护理中心大多数新诊断的肾脏肿瘤的首选治疗方法。向器官保留方法的转变主要是由于对肾脏功能的全球重要性有了更好的理解,以及肾脏手术对非肿瘤发病率和死亡率的影响。本文除了回顾评估肾脏功能的方法外,还讨论了各种保留肾单位技术在保护肾脏功能和改善非肿瘤预后方面的有效性。