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非囊性纤维化支气管扩张症

Non-cystic fibrosis bronchiectasis.

作者信息

Al Subie Haya, Fitzgerald Dominic A

机构信息

Department of Respiratory Medicine, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.

出版信息

J Paediatr Child Health. 2012 May;48(5):382-8. doi: 10.1111/j.1440-1754.2010.01871.x. Epub 2010 Oct 6.

Abstract

Non-cystic fibrosis (CF) bronchiectasis is said to be a declining problem in developed countries, although its prevalence in indigenous communities in Australia and New Zealand is among the highest reported in the world. Early childhood pneumonia and underlying conditions such as immunodeficiency and primary ciliary dyskinesia need to be considered in the aetiology. A high-resolution computerised tomography scan is the key investigation in children with a chronic wet cough in whom bronchiectasis is suspected. Regardless of the cause, the treatment of bronchiectasis is centred upon facilitating the clearance of airway secretions and the treatment of pulmonary exacerbations. This review aims to provide general paediatricians with an update on the presenting features, investigation and management of non-cystic fibrosis bronchiectasis.

摘要

非囊性纤维化(CF)支气管扩张在发达国家据说已成为一个逐渐减少的问题,尽管其在澳大利亚和新西兰原住民社区的患病率是世界上报道的最高之一。病因方面需要考虑幼儿期肺炎以及免疫缺陷和原发性纤毛运动障碍等潜在疾病。对于怀疑有支气管扩张的慢性湿性咳嗽儿童,高分辨率计算机断层扫描是关键检查。无论病因如何,支气管扩张的治疗都以促进气道分泌物清除和治疗肺部加重为中心。本综述旨在为普通儿科医生提供关于非囊性纤维化支气管扩张的临床表现、检查和管理的最新信息。

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