Department of Microbiology, Wing Hall, Cornell University, Ithaca, NY 14853-8101, USA.
J Bacteriol. 2011 Jan;193(2):575-9. doi: 10.1128/JB.01193-10. Epub 2010 Nov 19.
σ(D) proteins from Aeribacillus pallidus AC6 and Bacillus subtilis bound specifically, albeit weakly, to promoter DNA even in the absence of core RNA polymerase. Binding required a conserved CG motif within the -10 element, and this motif is known to be recognized by σ region 2.4 and critical for promoter activity.
来自苍白杆菌 AC6 和枯草芽孢杆菌的σ(D)蛋白即使在没有核心 RNA 聚合酶的情况下也能特异性地(尽管较弱地)结合到启动子 DNA 上。结合需要-10 元件内的保守 CG 基序,该基序已知被σ区 2.4 识别,并且对启动子活性至关重要。