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西咪替丁在住院患者中的应用。

The use of cimetidine in hospitalized patients.

出版信息

Can Fam Physician. 1984 Jan;30:69-72.

Abstract

Cimetidine is the most commonly prescribed drug in North America. A clinical review was conducted to identify physicians' prescribing habits. From September 1, 1981 to March 31, 1982, the charts were reviewed of 50 patients receiving cimetidine in an isolated coastal community hospital in British Columbia. It was discovered that physicians prescribed the drug for reasons approved by the Food and Drug Administration (FDA) only 14% of the time. The FDA guidelines approve cimetidine for duodenal ulcer, Zollinger-Ellison syndrome, and other hypersecretory states. A literature review was conducted, and guidelines on prescribing cimetidine were given to all members of the hospital's medical staff.

摘要

西咪替丁是北美最常开的处方药物。我们进行了一项临床审查,以确定医生的开药习惯。1981 年 9 月 1 日至 1982 年 3 月 31 日,我们审查了不列颠哥伦比亚省一个沿海社区医院中 50 名接受西咪替丁治疗的患者的病历。结果发现,医生开药的理由仅 14%得到了食品和药物管理局 (FDA) 的批准。FDA 指南仅批准西咪替丁用于十二指肠溃疡、卓-艾综合征和其他高分泌状态。我们进行了文献回顾,并向医院全体医务人员提供了西咪替丁处方指南。

相似文献

1
The use of cimetidine in hospitalized patients.
Can Fam Physician. 1984 Jan;30:69-72.
3
Cimetidine. H2-receptor blockade in gastrointestinal disease.
Arch Intern Med. 1978 Aug;138(8):1257-60. doi: 10.1001/archinte.138.8.1257.
4
Cimetidine pharmacokinetics in patients with Zollinger-Ellison syndrome.
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Zollinger-Ellison syndrome unresponsive to cimetidine.
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H2 receptor antagonists.
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7
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10
Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome.
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本文引用的文献

1
The use of drugs for unlabeled indications.
JAMA. 1980 Apr 18;243(15):1543-6.
2
The modern treatment of peptic ulceration.
Practitioner. 1981 Oct;225(1360):1371-6.
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Cimetidine in elderly patients: review of uses and risks.
J Am Geriatr Soc. 1982 Mar;30(3):170-3. doi: 10.1111/j.1532-5415.1982.tb01299.x.
5
Predictors of duodenal ulcer healing and relapse.
Gastroenterology. 1981 Dec;81(6):1061-7.
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Cimetidine, metoclopramide, or placebo in the treatment of symptomatic gastroesophageal reflux.
J Clin Gastroenterol. 1980 Jun;2(2):149-56. doi: 10.1097/00004836-198006000-00008.
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How physicians use cimetidine: a survey of hospitalized patients and published cases.
N Engl J Med. 1981 May 21;304(21):1281-4. doi: 10.1056/NEJM198105213042109.
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Does treatment with cimetidine extended beyond initial healing of duodenal ulcer reduce the subsequent relapse rate?
Br Med J (Clin Res Ed). 1982 Feb 27;284(6316):621-3. doi: 10.1136/bmj.284.6316.621.
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Cimetidine: II. Adverse reactions and patterns of use.
Ann Intern Med. 1982 Nov;97(5):728-34. doi: 10.7326/0003-4819-97-5-728.

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