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临床 O4:K12 血清型副溶血性弧菌 10329 株的基因组序列。

Genome sequence of the clinical O4:K12 serotype Vibrio parahaemolyticus strain 10329.

机构信息

Center for Food Safety and Applied Nutrition, Food andDrug Administration, College Park, MD 20740, USA.

出版信息

J Bacteriol. 2011 Jul;193(13):3405-6. doi: 10.1128/JB.05044-11. Epub 2011 May 6.

Abstract

Vibrio parahaemolyticus is the leading cause of food-borne illnesses worldwide. Here, we report a draft genome of V. parahaemolyticus strain 10329 of the O4:K12 serotype. It belongs to the main U.S. West Coast clonal complex of V. parahaemolyticus (sequence type 36 [ST36]) causing oyster-associated human illness. It contains the virulence determinants tdh and trh but appears to infect at much lower doses than V. parahaemolyticus strains with these same determinants from other areas, such as the U.S. Gulf and Atlantic coasts.

摘要

副溶血性弧菌是全世界食源性疾病的主要致病菌。本研究报道了一株 O4:K12 血清型副溶血性弧菌 10329 菌株的草图基因组。它属于美国西海岸主要的副溶血性弧菌克隆复合体(序列型 36[ST36]),可引起与牡蛎相关的人类疾病。它含有毒力决定因子 tdh 和 trh,但似乎比来自美国海湾和大西洋沿岸等其他地区的具有相同决定因子的副溶血性弧菌菌株感染剂量要低得多。

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