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单纯超声乳化白内障手术后患者光学相干断层扫描诊断术后囊样黄斑水肿的患病率。

Prevalence of optical coherence tomography-diagnosed postoperative cystoid macular oedema in patients following uncomplicated phaco-emulsification cataract surgery.

机构信息

Department of Clinical Vision Sciences, School of Allied Health, La Trobe University Eye Surgery Associates, Melbourne, VIC 3086, Australia.

出版信息

Clin Exp Ophthalmol. 2012 Apr;40(3):282-7. doi: 10.1111/j.1442-9071.2011.02638.x. Epub 2011 Sep 2.

Abstract

BACKGROUND

Postoperative cystoid macular oedema is a complication of uneventful cataract surgery. Whereas improved surgical techniques have decreased the incidence of cystoid macular oedema, it remains a cause of unfavourable visual outcome following surgery. Fundus fluorescein angiography has been the 'gold standard' for diagnosing subclinical cystoid macular oedema; however, non-invasive cross-sectional imaging of the retina with optical coherence tomography may be equally effective at detecting the condition and offers the ability to quantify and repeat results over time.

DESIGN

Prospective pre-post case series of patients undergoing routine phaco-emulsification surgery.

PARTICIPANTS

Eighty consecutive patients (100 eyes) with cataracts and an age range of 40 to 90 years (mean 76.18).

METHODS

Macular thickness of participants was determined using time-domain optical coherence tomography preoperatively and after surgery at 1 day, 1 week, 4 weeks and 6 months. Optical coherence tomography was used to diagnose postoperative cystoid macular oedema.

MAIN OUTCOME MEASURES

Presence of cysts at the macula, identified by optical coherence tomography, in addition to foveal and macular thickness (µm).

RESULTS

Cystoid macular oedema was present in 5% of eyes. Macular thickness increased after surgery and central foveal thickness increased by almost 7% but returned to preoperative levels after 6 months. Findings also indicate that patients who developed postoperative cystoid macular oedema had significantly thicker central foveal thickness of approximately 5% compared with those that did not.

CONCLUSIONS

Optical coherence tomography is a useful, non-invasive diagnostic tool in determining subclinical cystoid macular oedema in uncomplicated cataract surgery patients and detects the presence of retinal thickening and intra-retinal cysts very soon after surgery, thereby facilitating earlier diagnosis and treatment of postoperative cystoid macular oedema.

摘要

背景

术后囊样黄斑水肿是白内障手术无并发症的一种并发症。虽然改进的手术技术降低了囊样黄斑水肿的发生率,但它仍然是手术后视力不良的原因。眼底荧光血管造影一直是诊断亚临床囊样黄斑水肿的“金标准”;然而,视网膜的非侵入性横截面成像(光学相干断层扫描)在检测这种情况方面可能同样有效,并能够随着时间的推移定量和重复结果。

设计

对接受常规超声乳化白内障手术的患者进行前瞻性前后病例系列研究。

参与者

80 例连续患者(100 只眼),年龄在 40 至 90 岁之间(平均 76.18 岁)。

方法

使用时域光学相干断层扫描术在术前和术后 1 天、1 周、4 周和 6 个月时测量参与者的黄斑厚度。使用光学相干断层扫描术诊断术后囊样黄斑水肿。

主要观察指标

光学相干断层扫描术识别的黄斑处的囊肿,以及黄斑和中心凹厚度(µm)。

结果

5%的眼出现囊样黄斑水肿。手术后黄斑厚度增加,中心凹厚度增加近 7%,但 6 个月后恢复到术前水平。研究结果还表明,与未发生术后囊样黄斑水肿的患者相比,发生术后囊样黄斑水肿的患者的中心凹厚度显著增加了约 5%。

结论

光学相干断层扫描术是一种有用的、非侵入性的诊断工具,可用于确定无并发症白内障手术患者的亚临床囊样黄斑水肿,并在手术后不久即可检测到视网膜增厚和视网膜内囊肿的存在,从而促进术后囊样黄斑水肿的早期诊断和治疗。

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