Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ankara University, Ankara, Turkey.
Med Princ Pract. 2011;20(5):470-6. doi: 10.1159/000327658. Epub 2011 Jul 11.
The aim of this study was to compare the postoperative analgesic effects of preoperative intravenous (i.v.) paracetamol, diclofenac sodium and lornoxicam (nonsteroidal anti-inflammatory drugs).
Sixty patients with impacted third molar who underwent surgical removal were randomly allocated into three groups: group P (n = 20), group D (n = 20) and group L (n = 20). Group P received preoperatively 1 g paracetamol i.v., group D 75 mg diclofenac sodium i.m. and group L 8 mg lornoxicam i.v. Postoperative pain intensity, additional consumption of analgesics postoperatively and postoperative complications were compared among groups.
The groups were comparable for pain scores (p > 0.05). Maximum pain scores were recorded in postoperative 4th h in all groups (group L 22, 14-44 mm; group P 24, 13-43 mm; group D 14, 10-24 mm, p = 0.117). Patients experienced high satisfaction scores which were comparable among groups (group L 85, 75-100 mm; group P 87, 70-95 mm; group D 84, 77-98 mm, p = 0.457).
Preoperative intramuscular diclofenac, intravenous paracetamol and lornoxicam effectively decreased the pain scores. The patients were satisfied with the three postoperative pain management regimens.
本研究旨在比较术前静脉注射(IV)扑热息痛、双氯芬酸钠和洛索洛芬(非甾体抗炎药)的术后镇痛效果。
60 例接受第三磨牙拔除术的患者被随机分为三组:P 组(n=20)、D 组(n=20)和 L 组(n=20)。P 组术前给予 1g 扑热息痛 IV,D 组给予 75mg 双氯芬酸钠 IM,L 组给予 8mg 洛索洛芬 IV。比较三组术后疼痛强度、术后额外使用镇痛药和术后并发症。
三组疼痛评分无差异(p>0.05)。所有组在术后第 4 小时记录到最大疼痛评分(L 组 22,14-44mm;P 组 24,13-43mm;D 组 14,10-24mm,p=0.117)。患者的满意度评分较高,三组之间无差异(L 组 85,75-100mm;P 组 87,70-95mm;D 组 84,77-98mm,p=0.457)。
术前肌内注射双氯芬酸钠、静脉注射扑热息痛和洛索洛芬均可有效降低疼痛评分。三种术后疼痛管理方案患者均满意。