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["组学"在生物修复中的应用——综述]

[Application of "omics" in bioremediation--a review].

作者信息

Lv Yihua, Tian Yun, Zheng Tianling

机构信息

Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems, School of Life Sciences, Xiamen University, Xiamen 361005, China.

出版信息

Wei Sheng Wu Xue Bao. 2011 May;51(5):579-85.

Abstract

Environmental pollutants are a major concern worldwide. Bioremediation mediated by microorganisms is a highly promising technology that is environmentally friendly, safe and effective. However, successful execution of these bioremediation strategies requires a complete understanding of factors governing the growth, metabolism, dynamics and functions of indigenous microbial communities at contaminated sites. The combination of genomics, transcriptomics, proteomics and metabolomics has provided a crucial insight into microbial communities and their mechanisms in bioremediation of polluted environment. This current review is focused on application of these technologies in bioremediation at contaminated sites. Limitations of each "-omics" analysis are briefly discussed and integration of these "-omics" technologies in study the processes of harmful algal bloom and the microbial degradation metabolism of organic pollutants are presented.

摘要

环境污染物是全球主要关注的问题。由微生物介导的生物修复是一项极具前景的技术,具有环境友好、安全且有效的特点。然而,要成功实施这些生物修复策略,需要全面了解影响受污染场地中本地微生物群落生长、代谢、动态和功能的因素。基因组学、转录组学、蛋白质组学和代谢组学的结合为深入了解微生物群落及其在污染环境生物修复中的机制提供了关键见解。本综述聚焦于这些技术在受污染场地生物修复中的应用。简要讨论了每种“组学”分析的局限性,并介绍了这些“组学”技术在研究有害藻华过程和有机污染物的微生物降解代谢中的整合情况。

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