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社区居住的男性和女性发生非外伤性骨折后的住院情况。

Institutionalization following incident non-traumatic fractures in community-dwelling men and women.

机构信息

Division of General Internal Medicine, McGill University Health Center (MUHC), 1650 Cedar Ave., Montreal, QC, Canada.

出版信息

Osteoporos Int. 2012 Sep;23(9):2381-6. doi: 10.1007/s00198-011-1815-7. Epub 2011 Oct 19.

Abstract

UNLABELLED

Institutionalization after hip fracture occurs in at least 30% of patients in the year following hospital discharge. We demonstrate that the risk of transfer to a long-term care facility, after adjustment for age and burden of co-morbidity, is also increased following fractures at other osteoporotic sites in men and women. For most fractures, men are at greater risk than women.

INTRODUCTION

High institutionalization rates have been documented following non-traumatic hip fractures; however, there is lack of knowledge regarding the frequency of transfer to long-term care institutions of patients who sustain such fractures at other anatomical sites.

METHODS

Using the comprehensive health care databases of the province of Manitoba, Canada, we performed a retrospective matched cohort study of community-dwelling men and women aged 50 years and older who sustained an incident non-traumatic fracture between April 1, 1986, and March 31, 2006. Using Cox proportional hazards regression analysis, we estimated the sex-specific relative risk of transfers to long-term care institutions in the year following fracture at osteoporotic sites.

RESULTS

We identified a total of 70,264 individuals with incident fractures (70.0% in women) among whom 3,996 new admissions to long-term care institutions were documented in the year following the index fracture. New admissions increased over time (p < 0.0001 for temporal trends). The age- and co-morbidity-adjusted hazard ratio (HR) of institutionalization following a hip fracture was 4.89 (95% confidence interval [CI], 4.19 to 5.69) in men, and this risk was consistently at least twice that of controls for all other fracture sites (all p < 0.0001). In women, the relative risks were highest subsequent to a hip (HR, 2.79; 95% CI, 2.56 to 3.04) or vertebral fracture (HR, 2.18; 95% CI, 1.82 to 2.62).

CONCLUSIONS

Non-traumatic fractures at any site have serious consequences, including institutionalization. Men are at greater risk of transfer to long-term care following fracture than women.

摘要

背景

髋部骨折患者在出院后至少有 30%会出现院内康复。我们证明,男性和女性在其他骨质疏松性部位发生骨折后,即使在调整年龄和合并症负担后,入住长期护理机构的风险也会增加。对于大多数骨折,男性的风险高于女性。

目的

髋部非外伤性骨折后,机构化率较高,但是,对于在其他解剖部位发生此类骨折的患者,转入长期护理机构的频率知之甚少。

方法

我们使用加拿大曼尼托巴省的综合医疗保健数据库,对 1986 年 4 月 1 日至 2006 年 3 月 31 日期间年龄在 50 岁及以上、发生非外伤性骨折的社区居民进行了回顾性匹配队列研究。使用 Cox 比例风险回归分析,我们估计了在骨质疏松性部位发生骨折后一年内,转入长期护理机构的性别特异性相对风险。

结果

我们共确定了 70264 名发生骨折的个体(女性占 70.0%),其中在索引骨折后 1 年内,有 3996 名新入住长期护理机构。新入院人数随时间增加(时间趋势 p<0.0001)。髋部骨折后,经年龄和合并症调整的入院风险比(HR)为男性 4.89(95%置信区间[CI],4.19 至 5.69),这一风险始终至少是所有其他骨折部位对照的两倍(均 p<0.0001)。在女性中,随后发生髋部(HR,2.79;95%CI,2.56 至 3.04)或椎体骨折(HR,2.18;95%CI,1.82 至 2.62)的相对风险最高。

结论

任何部位的非外伤性骨折都会带来严重后果,包括机构化。男性在骨折后转入长期护理的风险高于女性。

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