Division of General Internal Medicine, McGill University Health Center (MUHC), 1650 Cedar Ave., Montreal, QC, Canada.
Osteoporos Int. 2012 Sep;23(9):2381-6. doi: 10.1007/s00198-011-1815-7. Epub 2011 Oct 19.
Institutionalization after hip fracture occurs in at least 30% of patients in the year following hospital discharge. We demonstrate that the risk of transfer to a long-term care facility, after adjustment for age and burden of co-morbidity, is also increased following fractures at other osteoporotic sites in men and women. For most fractures, men are at greater risk than women.
High institutionalization rates have been documented following non-traumatic hip fractures; however, there is lack of knowledge regarding the frequency of transfer to long-term care institutions of patients who sustain such fractures at other anatomical sites.
Using the comprehensive health care databases of the province of Manitoba, Canada, we performed a retrospective matched cohort study of community-dwelling men and women aged 50 years and older who sustained an incident non-traumatic fracture between April 1, 1986, and March 31, 2006. Using Cox proportional hazards regression analysis, we estimated the sex-specific relative risk of transfers to long-term care institutions in the year following fracture at osteoporotic sites.
We identified a total of 70,264 individuals with incident fractures (70.0% in women) among whom 3,996 new admissions to long-term care institutions were documented in the year following the index fracture. New admissions increased over time (p < 0.0001 for temporal trends). The age- and co-morbidity-adjusted hazard ratio (HR) of institutionalization following a hip fracture was 4.89 (95% confidence interval [CI], 4.19 to 5.69) in men, and this risk was consistently at least twice that of controls for all other fracture sites (all p < 0.0001). In women, the relative risks were highest subsequent to a hip (HR, 2.79; 95% CI, 2.56 to 3.04) or vertebral fracture (HR, 2.18; 95% CI, 1.82 to 2.62).
Non-traumatic fractures at any site have serious consequences, including institutionalization. Men are at greater risk of transfer to long-term care following fracture than women.
髋部骨折患者在出院后至少有 30%会出现院内康复。我们证明,男性和女性在其他骨质疏松性部位发生骨折后,即使在调整年龄和合并症负担后,入住长期护理机构的风险也会增加。对于大多数骨折,男性的风险高于女性。
髋部非外伤性骨折后,机构化率较高,但是,对于在其他解剖部位发生此类骨折的患者,转入长期护理机构的频率知之甚少。
我们使用加拿大曼尼托巴省的综合医疗保健数据库,对 1986 年 4 月 1 日至 2006 年 3 月 31 日期间年龄在 50 岁及以上、发生非外伤性骨折的社区居民进行了回顾性匹配队列研究。使用 Cox 比例风险回归分析,我们估计了在骨质疏松性部位发生骨折后一年内,转入长期护理机构的性别特异性相对风险。
我们共确定了 70264 名发生骨折的个体(女性占 70.0%),其中在索引骨折后 1 年内,有 3996 名新入住长期护理机构。新入院人数随时间增加(时间趋势 p<0.0001)。髋部骨折后,经年龄和合并症调整的入院风险比(HR)为男性 4.89(95%置信区间[CI],4.19 至 5.69),这一风险始终至少是所有其他骨折部位对照的两倍(均 p<0.0001)。在女性中,随后发生髋部(HR,2.79;95%CI,2.56 至 3.04)或椎体骨折(HR,2.18;95%CI,1.82 至 2.62)的相对风险最高。
任何部位的非外伤性骨折都会带来严重后果,包括机构化。男性在骨折后转入长期护理的风险高于女性。