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水胶体敷料在部分厚度烧伤中的应用减少了植皮:水胶体敷料与磺胺嘧啶银的比较。

Reduction in skin grafting after the introduction of hydrofiber dressings in partial thickness burns: a comparison between a hydrofiber and silver sulphadiazine.

机构信息

Department of Surgery, Burn Centre, Maasstad Hospital, Rotterdam, The Netherlands.

出版信息

Burns. 2013 Feb;39(1):130-5. doi: 10.1016/j.burns.2012.03.004. Epub 2012 Apr 4.

Abstract

AIM/PURPOSE: The aim of this study was to compare clinical outcome of children with scald burns treated with a hydrofiber dressing (Aquacel(®), Convatec Inc.) with the former standard of care with silver sulfadiazine (Flammazine(®); Solvay Pharmaceuticals), considering surgical intervention and length of stay (LOS).

METHODS

A retrospective study of all consecutive children from zero to four years with primary scald burns up to 10% admitted to the Burn Centre of the Maasstad Hospital Rotterdam between January 1987 and January 2010 were reviewed. For data collection a prospective computerized database was used. For comparison the study period was divided into two periods representing the period before and after the introduction of the hydrofiber dressing (HFD), respectively 1987-1999 (period 1) and 1999-2010 (period 2).

RESULTS

Over the whole study period 27.3% of 502 patients treated with silver sulfadiazine (Ag-SD) underwent surgery, while before the introduction of HFD 30.5% of 338 Ag-SD treated patients were operated upon. After the introduction of the HFD 20.7% of 164 patients treated with Ag-SD eventually underwent skin grafting, a significant difference with the 11.6% of 302 patients whose wounds were dressed with HFD (p<0.01).

CONCLUSIONS

Compared to silver sulfadiazine treatment a reduced number of surgical interventions was observed in mixed partial thickness scald burns up to 10% TBSA burned in children aged 0-4 years after the introduction of hydrofiber dressings. The mode of treatment with this wound dressing also limited hospital length of stay.

摘要

目的

本研究旨在比较用水胶体敷料(Aquacel ® ,康维德公司)治疗小儿烫伤与磺胺嘧啶银(Flammazine ® ;索尔维制药公司)的临床疗效,观察手术干预和住院时间(LOS)的变化。

方法

回顾性分析 1987 年 1 月至 2010 年 1 月期间在鹿特丹马斯塔德医院烧伤中心收治的 0 至 4 岁、接受首次治疗的原发性面积达 10%的儿童烫伤患者。为了数据收集,使用了一个前瞻性的计算机数据库。为了比较,将研究期间分为两个时期,分别代表水胶体敷料引入前(1987-1999 年)和引入后(1999-2010 年)。

结果

在整个研究期间,502 例磺胺嘧啶银治疗患者中 27.3%接受了手术,而在水胶体敷料引入前,338 例磺胺嘧啶银治疗患者中有 30.5%接受了手术。在水胶体敷料引入后,164 例磺胺嘧啶银治疗患者中有 20.7%最终接受了植皮手术,与 302 例用水胶体敷料治疗的患者(11.6%)相比,差异有统计学意义(p<0.01)。

结论

与磺胺嘧啶银治疗相比,在 0-4 岁、面积达 10%TBSA 的儿童混合部分厚度烫伤中,引入水胶体敷料后,手术干预的数量减少。这种伤口敷料的治疗方式也限制了住院时间。

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