Department of Rehabilitation, Nursing Science and Sports, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, the Netherlands.
Nurs Res. 2012 Sep-Oct;61(5):333-41. doi: 10.1097/NNR.0b013e31825d9e9e.
Although poststroke depression has a significant impact on a patient's ability to recover after stroke, it is generally not recognized. Structured screening can help nurses identify symptoms of depression in stroke patients. In clinical practice, the utility of an instrument is as importantas its validity and reliability.
To investigate the reliability, validity, and clinical utility of the nine-item and two-item patient health questionnaires (PHQ-9 and PHQ-2, respectively) in stroke patients in a clinical nursing setting. The results of these questionnaires will be compared against those from the Geriatric Depression Scale.
The PHQ-9 was administered by 43 ward nurses in 55 patients with an intracerebral hemorrhage or ischemic infarction who were able to communicate adequately. The interrater reliability, test-retest reliability and internal consistency, concurrent validity, diagnostic accuracy, and clinical utility were evaluated.
The interrater reliability (intraclass correlation [ICC] = 0.98, 95% CI [0.96, 0.99]), test-retest reliability (ρ(Sp) = 0.75, p < .001), and internal consistency (Cronbach's α = 0.79) of the PHQ-9 were good. The concurrent validity was moderate for the PHQ-9, with a Pearson's correlation of .7 (p < .001) and acceptable for the PHQ-2 with a Pearson's correlation of .8 (p < .01). The optimum cutoff point of the PHQ-9 for major depression was 10 (sensitivity, 100%; specificity,86%; positive predicted value, 50%; and negative predicted value, 100%). For the PHQ-2, the optimum cutoff point was 2 (sensitivity, 100%; specificity, 77%; positive predicted value, 38%; and negative predicted value, 100%).
The PHQ is a brief and easy-to-use instrument for nursing practice. It shows good reliability, validity, and clinical utility when used in stroke patients who are able to communicate adequately.
尽管卒中后抑郁会显著影响患者的卒中后康复能力,但它通常未被识别。结构化筛查可以帮助护士识别卒中患者的抑郁症状。在临床实践中,工具的实用性与有效性和可靠性同样重要。
在临床护理环境中,调查九项和两项患者健康问卷(PHQ-9 和 PHQ-2)在卒中患者中的可靠性、有效性和临床实用性。这些问卷的结果将与老年抑郁量表的结果进行比较。
43 名病房护士对 55 名能够充分沟通的脑出血或缺血性梗死患者进行 PHQ-9 评估。评估了其评分者间信度、重测信度和内部一致性、同时效度、诊断准确性和临床实用性。
PHQ-9 的评分者间信度(组内相关系数 [ICC] = 0.98,95%置信区间 [0.96,0.99])、重测信度(ρ(Spearman)= 0.75,p <.001)和内部一致性(克朗巴赫 α = 0.79)良好。PHQ-9 的同时效度为中度,Pearson 相关系数为.7(p <.001),PHQ-2 的同时效度为可接受,Pearson 相关系数为.8(p <.01)。PHQ-9 用于诊断重度抑郁的最佳截断点为 10(灵敏度 100%;特异性 86%;阳性预测值 50%;阴性预测值 100%)。对于 PHQ-2,最佳截断点为 2(灵敏度 100%;特异性 77%;阳性预测值 38%;阴性预测值 100%)。
PHQ 是一种简短易用的护理工具。它在能够充分沟通的卒中患者中具有良好的可靠性、有效性和临床实用性。