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免疫功能低下患者的腹泻。

Diarrhea in the immunocompromised patient.

机构信息

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

出版信息

Gastroenterol Clin North Am. 2012 Sep;41(3):677-701. doi: 10.1016/j.gtc.2012.06.009. Epub 2012 Jul 4.

Abstract

Diarrhea is a common problem in patients with immunocompromising conditions. The etiologic spectrum differs from patients with diarrhea who have a normal immune system. This article reviews the most important causes of diarrhea in immunocompromised patients, ranging from infectious causes to noninfectious causes of diarrhea in the setting of HIV infection as a model for other conditions of immunosuppression. It also deals with diarrhea in specific situations, eg, after hematopoietic stem cell or solid organ transplantation, diarrhea induced by immunosuppressive drugs, and diarrhea in congenital immunodeficiency syndromes.

摘要

腹泻是免疫功能低下患者的常见问题。病因谱与具有正常免疫系统的腹泻患者不同。本文以 HIV 感染为例,综述了免疫功能低下患者腹泻的最重要病因,包括感染性和非感染性病因,还涉及了特定情况下的腹泻,如造血干细胞或实体器官移植后、免疫抑制药物引起的腹泻以及先天性免疫缺陷综合征中的腹泻。

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