木糖醇漱口水对变形链球菌的影响。
Effects of xylitol mouthrinse on Streptococcus mutans.
机构信息
Faculty of Dentistry, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.
出版信息
J Dent. 2012 Dec;40(12):1151-4. doi: 10.1016/j.jdent.2012.08.014. Epub 2012 Sep 5.
OBJECTIVES
This study aimed to measure the effect of xylitol mouthrinse on salivary Streptococcus mutans counts.
METHODS
Subjects in the study group (n = 25) used xylitol mouthrinse for 4 weeks, while another group (n = 25) used saccharine mouthrinse. S. mutans were measured before and after intervention.
RESULTS
At the baseline the mean S. mutans scores were 3.9 (SE = 0.03) and 3.9 (0.04) for the xylitol group and control group respectively, while the scores were 2.8 (0.13) and 3.9 (0.07) after the intervention. Significant reductions (p < 0.01) in the scores of S. mutans were found after the four week use of xylitol mouthrinse.
CONCLUSIONS
Significant reductions in the scores of S. mutans were found after the four week use of 20% xylitol mouthrinse. The bacteriostatic effect of xylitol mouthrinse on S. mutans may be comparable to other xylitol products. Further studies are needed to confirm both the short and long term effects of xylitol mouthrinse.
目的
本研究旨在测量木糖醇漱口液对唾液变形链球菌计数的影响。
方法
研究组（n=25）使用木糖醇漱口液 4 周，另一组（n=25）使用糖精漱口液。干预前后测量变形链球菌。
结果
基线时，木糖醇组和对照组的变形链球菌评分分别为 3.9（SE=0.03）和 3.9（0.04），干预后分别为 2.8（0.13）和 3.9（0.07）。使用木糖醇漱口液 4 周后，变形链球菌评分显著降低（p<0.01）。
结论
使用 20%木糖醇漱口液 4 周后，变形链球菌评分显著降低。木糖醇漱口液对变形链球菌的抑菌作用可能与其他木糖醇产品相当。需要进一步研究来证实木糖醇漱口液的短期和长期效果。
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