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探讨生活质量与跌倒风险、认知功能和日常功能之间的关联,采用 EQ-5D 和 ICECAP-O 评估工具,研究对象为行动不便的老年人。

Exploration of the association between quality of life, assessed by the EQ-5D and ICECAP-O, and falls risk, cognitive function and daily function, in older adults with mobility impairments.

机构信息

Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, The University of British Columbia, Research Pavilion, 7th floor, 828 West 10th Avenue, V5Z 1M9, Vancouver, BC, Canada.

出版信息

BMC Geriatr. 2012 Oct 24;12:65. doi: 10.1186/1471-2318-12-65.

Abstract

BACKGROUND

Our research sought to understand how falls risk, cognitive function, and daily function are associated with health related quality of life (using the EuroQol-5D) and quality of life (using the ICECAP-O) among older adults with mobility impairments.

METHODS

The EQ-5D and ICECAP-O were administered at 12 months post first clinic attendance at the Vancouver Falls Prevention Clinic. We report descriptive statistics for all baseline characteristics collected at first clinic visit and primary outcomes of interest. Using multivariate stepwise linear regression, we assessed the construct validity of the EQ-5D and ICECAP-O using three dependent measures that are recognized indicators of "impaired mobility" - physiological falls risk, general balance and mobility, and cognitive status among older adults.

RESULTS

We report data on 215 seniors who attended the Vancouver Falls Prevention Clinic and received their first clinic assessment. Patients had a mean age of 79.3 (6.2) years. After accounting for known covariates (i.e., age and sex), the ICECAP-O domains explained a greater amount of variation in each of the three dependent measures compared with the EQ-5D domains.

CONCLUSION

Both the EQ-5D and ICECAP-O demonstrate associations with falls risk and general balance and mobility; however, only the ICECAP-O was associated with cognitive status among older adults with mobility impairments.

TRIAL REGISTRATION

ClinicalTrials.gov Identifier: NCT01022866.

摘要

背景

我们的研究旨在了解在有行动障碍的老年人中,跌倒风险、认知功能和日常功能与健康相关生活质量(使用 EQ-5D)和生活质量(使用 ICECAP-O)之间的关系。

方法

在温哥华跌倒预防诊所首次就诊后 12 个月,对 EQ-5D 和 ICECAP-O 进行了管理。我们报告了在首次就诊时收集的所有基线特征和主要研究结果的描述性统计数据。使用多元逐步线性回归,我们使用三种公认的“行动障碍”指标——生理跌倒风险、总体平衡和移动能力以及认知状态,评估了 EQ-5D 和 ICECAP-O 的结构效度。

结果

我们报告了 215 名参加温哥华跌倒预防诊所并接受首次诊所评估的老年人的数据。患者的平均年龄为 79.3(6.2)岁。在考虑到已知的协变量(即年龄和性别)后,与 EQ-5D 域相比,ICECAP-O 域解释了三个依赖变量中每个变量的更大变化。

结论

EQ-5D 和 ICECAP-O 都与跌倒风险和总体平衡与移动能力相关联;然而,只有 ICECAP-O 与有行动障碍的老年人的认知状态相关联。

试验注册

ClinicalTrials.gov 标识符:NCT01022866。

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