Ogunleye O O, Ogundele S O, Akinyemi J O, Ogbera A O
Department of Medicine, Lagos State University College of Medicine and Teaching Hospital, Lagos, Nigeria.
Afr J Med Med Sci. 2012 Jun;41(2):191-5.
The clustering of cardiovascular risk factors and diseases has grievous implications on overall morbidity and mortality. There is however relative paucity of this information among the Nigerian population. This study was aimed at defining the prevalence of the clustering of hypertension (HT), diabetes mellitus (DM) and dyslipidemia (DYSL) in a Nigerian teaching hospital outpatient clinics population.
A cross sectional study of patients managed at the hypertension and diabetes clinics of the Lagos State University Teaching Hospital, Nigeria between January and December 2008. The baseline demographic characteristics, blood pressures, blood sugars and fasting lipid profiles were obtained retrospectively from hospital records. Using the standard criteria for the diagnosis of HT, DM and DYSL, the prevalence of these conditions and their respective clusters were determined.
A total of 506 patients were seen over this period, male; 234 (46.2%), female; 272(53.8%) with mean age of 57.35 (1.28) years. The prevalence of HT, DM and DYSL were 85%, 39.5% and 58.9% respectively. Concurrent HT and DYSL was the most prevalent cluster found in 146 patients (28.9%), followed by the clustering of the three co-morbidities of HT, DM and DYSL in 124 patients (24.5%).Other clusters were DM+HT; 49 (9.7%), DM+DYSL;13 (2.6%). 41.2% of the population had the clustering of at least two co-morbidities and about a quarter had the three conditions coexisting.
There is a significant burden of the cardiovascular risk factors occurring in clusters in the Nigerian population studied. This calls for purposeful measures to control these risk factors.
心血管危险因素和疾病的聚集对总体发病率和死亡率有严重影响。然而,尼日利亚人群中这方面的信息相对匮乏。本研究旨在确定尼日利亚一家教学医院门诊患者中高血压(HT)、糖尿病(DM)和血脂异常(DYSL)聚集的患病率。
对2008年1月至12月在尼日利亚拉各斯州立大学教学医院高血压和糖尿病门诊接受治疗的患者进行横断面研究。回顾性地从医院记录中获取基线人口统计学特征、血压、血糖和空腹血脂谱。采用HT、DM和DYSL的诊断标准,确定这些疾病及其各自聚集情况的患病率。
在此期间共诊治506例患者,男性234例(46.2%),女性272例(53.8%),平均年龄57.35(1.28)岁。HT、DM和DYSL的患病率分别为85%、39.5%和58.9%。HT和DYSL同时存在是最常见的聚集情况,见于146例患者(28.9%),其次是HT、DM和DYSL三种合并症的聚集,见于124例患者(24.5%)。其他聚集情况为DM+HT;49例(9.7%),DM+DYSL;13例(2.6%)。41.2%的人群至少有两种合并症聚集,约四分之一的人群三种情况并存。
在所研究的尼日利亚人群中,心血管危险因素以聚集形式出现的负担很重。这需要采取有针对性的措施来控制这些危险因素。