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一项针对有抑郁症状青少年的基于计算机的认知行为疗法程序原型的试点双盲随机安慰剂对照试验。

A pilot double blind randomized placebo controlled trial of a prototype computer-based cognitive behavioural therapy program for adolescents with symptoms of depression.

作者信息

Stasiak Karolina, Hatcher Simon, Frampton Christopher, Merry Sally N

机构信息

University of Auckland,New Zealand.

University of Otago,Christchurch,New Zealand.

出版信息

Behav Cogn Psychother. 2014 Jul;42(4):385-401. doi: 10.1017/S1352465812001087. Epub 2012 Dec 20.

Abstract

BACKGROUND

Depressive disorder is common in adolescents and largely untreated. Computers offer a way of increasing access to care. Computerized therapy is effective for depressed adults but to date little has been done for depressed adolescents.

AIMS

The objective of this study was to examine the feasibility, acceptability, and effects of The Journey, a computerized cognitive behavioural therapy (cCBT) program for depressed adolescents.

METHOD

Thirty-four adolescents (mean age 15.2 years, SD = 1.5) referred by school counsellors were randomly assigned to either cCBT or a computer-administered attention placebo program with psychoeducational content (CPE). Participants completed the intervention at school. Data were collected at baseline, post-intervention and at a 1-month follow-up. The primary outcome measure was the Child Depression Rating Scale Revised (CDRS-R); secondary outcome measures were: RADS-2; Pediatric Quality of Life Inventory; Adolescent Coping Scale (short form); response and remission rates on CDRS-R. Completion rates and self-reported satisfaction ratings were used to assess feasibility and acceptabililty of the intervention.

RESULTS

Ninety-four percent of cCBT and 82% of CPE participants completed the intervention. Eighty-nine percent liked The Journey a lot or thought it was "okay" and 89% of them would recommend it for use with others as is or after some improvement. Adolescents treated with cCBT showed greater symptom improvement on CDRS-R than those treated with CPE program (mean change on cCBT = 17.6, CI = 14.13-21.00; CPE = 6.06, CI = 2.01-10.02; p< .001).

CONCLUSIONS

It is feasible, acceptable and efficacious to deliver computerized CBT to depressed adolescents in a school setting. Generalizability is limited by the size of the study.

摘要

背景

抑郁症在青少年中很常见,且大多未得到治疗。计算机提供了一种增加获得治疗机会的途径。计算机化治疗对成年抑郁症患者有效,但迄今为止针对青少年抑郁症患者的相关研究较少。

目的

本研究的目的是检验“旅程”(The Journey)这一针对青少年抑郁症的计算机化认知行为疗法(cCBT)项目的可行性、可接受性和效果。

方法

由学校辅导员转介的34名青少年(平均年龄15.2岁,标准差=1.5)被随机分配到cCBT组或接受包含心理教育内容的计算机管理注意力安慰剂项目(CPE)组。参与者在学校完成干预。在基线、干预后和1个月随访时收集数据。主要结局指标是儿童抑郁评定量表修订版(CDRS-R);次要结局指标包括:RADS-2;儿童生活质量量表;青少年应对量表(简表);CDRS-R的反应率和缓解率。完成率和自我报告的满意度评分用于评估干预的可行性和可接受性。

结果

94%的cCBT组参与者和82%的CPE组参与者完成了干预。89%的人非常喜欢“旅程”项目或认为它“还可以”,其中89%的人会推荐原样使用或在改进后供他人使用。接受cCBT治疗的青少年在CDRS-R上的症状改善程度高于接受CPE项目治疗的青少年(cCBT组的平均变化=17.6,置信区间=14.13 - 21.00;CPE组=6.06,置信区间=2.01 - 10.02;p<0.001)。

结论

在学校环境中为青少年抑郁症患者提供计算机化认知行为疗法是可行、可接受且有效的。本研究规模限制了结果的普遍性。

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