横断面研究显示，成年人总久坐时间和休闲屏幕时间与心血管代谢风险相关。挪威亨于尔特研究结果。
Cross-sectional associations of total sitting and leisure screen time with cardiometabolic risk in adults. Results from the HUNT Study, Norway.
机构信息
Prevention Research Collaboration, Sydney School of Public Health, University of Sydney, Australia.
Prevention Research Collaboration, Sydney School of Public Health, University of Sydney, Australia.
出版信息
J Sci Med Sport. 2014 Jan;17(1):78-84. doi: 10.1016/j.jsams.2013.03.004. Epub 2013 Apr 22.
OBJECTIVES
To examine associations of total sitting time, TV-viewing and leisure-time computer use with cardiometabolic risk biomarkers in adults.
DESIGN
Population based cross-sectional study.
METHODS
Waist circumference, BMI, total cholesterol, HDL cholesterol, blood pressure, non-fasting glucose, gamma glutamyltransferase (GGT) and triglycerides were measured in 48,882 adults aged 20 years or older from the Nord-Trøndelag Health Study 2006-2008 (HUNT3). Adjusted multiple regression models were used to test for associations between these biomarkers and self-reported total sitting time, TV-viewing and leisure-time computer use in the whole sample and by cardiometabolic disease status sub-groups.
RESULTS
In the whole sample, reporting total sitting time ≥10 h/day was associated with poorer BMI, waist circumference, total cholesterol, HDL cholesterol, diastolic blood pressure, systolic blood pressure, non-fasting glucose, GGT and triglyceride levels compared to those reporting total sitting time <4h/day (all p<0.05). TV-viewing ≥4 h/day was associated with poorer BMI, waist circumference, total cholesterol, HDL cholesterol, systolic blood pressure, GGT and triglycerides compared to TV-viewing <1h/day (all p<0.05). Leisure-time computer use ≥1 h/day was associated with poorer BMI, total cholesterol, diastolic blood pressure, GGT and triglycerides compared with those reporting no leisure-time computing. Sub-group analyses by cardiometabolic disease status showed similar patterns in participants free of cardiometabolic disease, while similar albeit non-significant patterns were observed in those with cardiometabolic disease.
CONCLUSIONS
Total sitting time, TV-viewing and leisure-time computer use are associated with poorer cardiometabolic risk profiles in adults. Reducing sedentary behaviour throughout the day and limiting TV-viewing and leisure-time computer use may have health benefits.
目的
探讨成年人总久坐时间、看电视时间和闲暇时间使用电脑与心血管代谢风险生物标志物的关系。
设计
基于人群的横断面研究。
方法
在 2006-2008 年诺尔兰健康研究（HUNT3）中，对 48882 名年龄在 20 岁及以上的成年人测量了腰围、BMI、总胆固醇、高密度脂蛋白胆固醇、血压、非空腹血糖、γ-谷氨酰转移酶（GGT）和甘油三酯。采用调整后的多元回归模型，检验了总久坐时间、看电视时间和闲暇时间使用电脑与整个样本以及心血管代谢疾病状态亚组中这些生物标志物之间的关系。
结果
在整个样本中，与报告每天总久坐时间<4 小时相比，报告每天总久坐时间≥10 小时与较差的 BMI、腰围、总胆固醇、高密度脂蛋白胆固醇、舒张压、收缩压、非空腹血糖、GGT 和甘油三酯水平相关（均 p<0.05）。每天看电视时间≥4 小时与较差的 BMI、腰围、总胆固醇、高密度脂蛋白胆固醇、收缩压、GGT 和甘油三酯水平相关，与每天看电视时间<1 小时相比（均 p<0.05）。每天闲暇时间使用电脑≥1 小时与较差的 BMI、总胆固醇、舒张压、GGT 和甘油三酯水平相关，与报告无闲暇时间使用电脑的人群相比（均 p<0.05）。按心血管代谢疾病状态进行亚组分析，在无心血管代谢疾病的参与者中观察到了相似的模式，而在患有心血管代谢疾病的参与者中观察到了类似但无统计学意义的模式。
结论
总久坐时间、看电视时间和闲暇时间使用电脑与成年人较差的心血管代谢风险特征相关。减少全天的久坐行为，并限制看电视时间和闲暇时间使用电脑可能对健康有益。
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