Schaub A, Neubauer N, Bernhard B, Born C, Möller H-J, Grunze H
Klinik für Psychiatrie und Psychotherapie, Ludwig-Maximilians-Universität, München, Germany.
Fortschr Neurol Psychiatr. 2013 May;81 Suppl 1:S30-4. doi: 10.1055/s-0033-1335242. Epub 2013 May 16.
52 patients with bipolar disorder were treated with psychopharmacotherapy and a cognitive psychoeducational group programme that was established at the Department of Psychiatry and Psychotherapy of the Ludwig Maximilian University, Munich, Germany. The programme covers psychoeducation, identifying and coping with depressive and manic symptoms, relapse prevention and establishing a stable life style. 96 % rated the group to be helpful and felt well informed about their illness. There were significant gains in knowledge (F = 25,714, p < 0.001) and improvements in the severity of the illness (CGI; F = 68,255, p < 0.001) post-treatment. With regard to sociodemographic and clinical variables, only the level of work qualification showed a differential treatment response: patients with higher qualifications had a more favourable course of the illness (F = 4,125, p = 0.048). At one and two year follow-up 25 % and, respectively, 30 % of the sample had to be readmitted. A higher number of previous hospitalisations (p = 0.010) and male sex (p = 0.031) turned out to be significant predictors of relapse (R² = 0.358, p = 0.004) at two year follow-up. This disorder-specific group programme represents a key component of treatment offering emotional support for patients and their relatives. Patients are to be involved in the treatment process and need information about the illness, its psychosocial and pharmacological treatment as well as help in learning practical skills to improve their living with the disease. Being integrated and committed to a supporting network may increase their quality of life.
52名双相情感障碍患者接受了心理药物治疗以及一项认知心理教育团体项目,该项目由德国慕尼黑路德维希 - 马克西米利安大学精神病学与心理治疗系设立。该项目涵盖心理教育、识别和应对抑郁及躁狂症状、预防复发以及建立稳定的生活方式。96%的患者认为该团体项目有帮助,并对自己的病情有了充分了解。治疗后,患者在知识方面有显著提高(F = 25,714,p < 0.001),病情严重程度也有所改善(临床总体印象量表;F = 68,255,p < 0.001)。在社会人口统计学和临床变量方面,只有工作资格水平显示出不同的治疗反应:资格较高的患者病情发展更为有利(F = 4,125,p = 0.048)。在一年和两年的随访中,分别有25%和30%的样本需要再次入院。在两年随访时,既往住院次数较多(p = 0.010)和男性(p = 0.031)被证明是复发的显著预测因素(R² = 0.358,p = 0.004)。这个针对特定疾病的团体项目是治疗的关键组成部分,为患者及其亲属提供情感支持。患者应参与治疗过程,需要了解疾病、其心理社会和药物治疗方面的信息,以及学习实用技能以改善与疾病共存状况的帮助。融入并致力于一个支持网络可能会提高他们的生活质量。