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使用三维径向梯度回波序列对短T2*自旋进行B1映射。

B1 mapping of short T2 * spins using a 3D radial gradient echo sequence.

作者信息

Kobayashi Naoharu, Garwood Michael

机构信息

Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.

出版信息

Magn Reson Med. 2014 May;71(5):1689-99. doi: 10.1002/mrm.24817. Epub 2013 Jun 10.

Abstract

PURPOSE

To develop a method to acquire a radiofrequency (B1 ) field map when the signal has a short T2 *.

THEORY AND METHODS

The method is based on the actual flip angle imaging (AFI) technique and a radial 3D gradient-echo sequence known as COncurrent Dephasing and Excitation (CODE), which preserves short T2 (*) signals. CODE was implemented with Gradient-modulated Offset-Independent Adiabaticity (GOIA) pulses to obtain high estimation sensitivity with AFI. The correlation method, which removes the quadratic phase from the frequency-modulated pulse excitation, was modified to handle gradient-modulated pulses. Validity of the modified correlation procedure was tested by Bloch simulations. CODE experiments with sinc, hyperbolic secant, and GOIA pulses were performed in order to see effects from the frequency and gradient modulation. Finally, GOIA-CODE AFI was conducted and compared with conventional AFI with 3D gradient echo (GRE).

RESULTS

The modified correlation method developed to accommodate frequency and gradient modulations of GOIA performed well as judged by the minimal impact on reconstructed image quality. GOIA-CODE AFI provided flip angle maps consistent with those measured by GRE AFI when the T2 * was long (>2 ms) and continued to perform well for short T2 * signals.

CONCLUSION

The proposed technique provides a means to obtain a 3D B1 field map when imaging spins with short T2 (*) .

摘要

目的

开发一种在信号具有短T2*时获取射频(B1)场图的方法。

理论与方法

该方法基于实际翻转角成像(AFI)技术和一种称为同时去相和激发(CODE)的径向三维梯度回波序列,它能保留短T2(*)信号。通过梯度调制的与偏移无关的绝热(GOIA)脉冲实现CODE,以获得AFI的高估计灵敏度。对从调频脉冲激发中去除二次相位的相关方法进行了修改,以处理梯度调制脉冲。通过布洛赫模拟测试了修改后的相关程序的有效性。进行了使用 sinc、双曲正割和GOIA脉冲的CODE实验,以观察频率和梯度调制的影响。最后,进行了GOIA-CODE AFI实验,并与传统的三维梯度回波(GRE)AFI进行了比较。

结果

所开发的用于适应GOIA频率和梯度调制的修改后的相关方法,对重建图像质量的影响最小,表现良好。当T2较长(>2 ms)时,GOIA-CODE AFI提供的翻转角图与GRE AFI测量的图一致,并且对于短T2信号也能持续良好地工作。

结论

所提出的技术提供了一种在对具有短T2(*)的自旋进行成像时获取三维B1场图的方法。

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