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胰腺癌的最新进展。

Recent progress in pancreatic cancer.

机构信息

Associate Professor, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD; Associate Professor, Department of Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD; Associate Professor, Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

CA Cancer J Clin. 2013 Sep;63(5):318-48. doi: 10.3322/caac.21190. Epub 2013 Jul 15.

Abstract

Pancreatic cancer is currently one of the deadliest of the solid malignancies. However, surgery to resect neoplasms of the pancreas is safer and less invasive than ever, novel drug combinations have been shown to improve survival, advances in radiation therapy have resulted in less toxicity, and enormous strides have been made in the understanding of the fundamental genetics of pancreatic cancer. These advances provide hope but they also increase the complexity of caring for patients. It is clear that multidisciplinary care that provides comprehensive and coordinated evaluation and treatment is the most effective way to manage patients with pancreatic cancer.

摘要

胰腺癌目前是实体恶性肿瘤中致死率最高的癌症之一。然而,与以往相比,现在用于切除胰腺肿瘤的手术更加安全、微创,新的药物联合治疗方案已被证实能够提高患者的生存率,放射治疗技术的进步降低了其毒性,人们对胰腺癌的基础遗传学也有了更深入的理解。这些进步带来了希望,但也增加了患者护理的复杂性。显然,多学科护理为患者提供全面、协调的评估和治疗,是管理胰腺癌患者的最有效方式。

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