Müller-Riemenschneider Falk, Pereira Gavin, Villanueva Karen, Christian Hayley, Knuiman Matthew, Giles-Corti Billie, Bull Fiona C
Saw Swee Hock School of Public Health and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Block MD3, 16 Medical Drive, Singapore 117597, Singapore.
BMC Public Health. 2013 Aug 15;13:755. doi: 10.1186/1471-2458-13-755.
Studies repeatedly highlight associations between the built environment and physical activity, particularly walking. Fewer studies have examined associations with cardiometabolic risk factors, with associations with obesity inconsistent and scarce evidence examining associations with other cardiometabolic risk factors. We aim to investigate the association between neighborhood walkability and the prevalence of obesity, hypertension, hypercholesterolaemia, and type-2 diabetes mellitus.
Cross-sectional study of 5,970 adults in Western Australia. Walkability was measured objectively for a 1,600 m and 800 m neighborhood buffer. Logistic regression was used to assess associations overall and by sex, adjusting for socio-demographic factors. Mediation by physical activity and sedentary behavior was investigated.
Individuals living in high compared with less walkable areas were less likely to be obese (1,600 m OR: 0.84, 95% CI: 0.7 to 1; 800 m OR: 0.75, 95% CI: 0.62 to 0.9) and had lower odds of type-2 diabetes mellitus at the 800 m buffer (800 m OR: 0.69, 95% CI: 0.51 to 0.93). There was little evidence for an association between walkability and hypertension or hypercholesterolaemia. The only significant evidence of any difference in the associations in men and women was a stronger association with type-2 diabetes mellitus at the 800 m buffer in men. Associations with obesity and diabetes attenuated when additionally adjusting for physical activity and sedentary behavior but the overall association with obesity remained significant at the 800 m buffer (800 m OR: 0.78, 95% CI: 0.64 to 0.96).
A protective association between neighborhood walkability and obesity was observed. Neighborhood walkability may also be protective of type-2 diabetes mellitus, particularly in men. No association with hypertension or hypercholesterolaemia was found. This warrants further investigation. Findings contribute towards the accumulating evidence that city planning and policy related strategies aimed at creating supportive environments could play an important role in the prevention of chronic diseases.
多项研究反复强调了建成环境与身体活动之间的关联,尤其是步行。较少有研究探讨其与心血管代谢危险因素的关联,与肥胖的关联并不一致,且缺乏关于与其他心血管代谢危险因素关联的证据。我们旨在研究邻里步行便利性与肥胖、高血压、高胆固醇血症及2型糖尿病患病率之间的关联。
对西澳大利亚州的5970名成年人进行横断面研究。对1600米和800米邻里缓冲区的步行便利性进行客观测量。采用逻辑回归评估总体及按性别划分的关联,并对社会人口学因素进行调整。研究身体活动和久坐行为的中介作用。
与步行便利性较差地区的居民相比,居住在步行便利性较高地区的居民肥胖的可能性较小(1600米缓冲区域:比值比[OR]为0.84,95%置信区间[CI]:0.7至1;800米缓冲区域:OR为0.75,95%CI:0.62至0.9),且在800米缓冲区域患2型糖尿病的几率较低(800米缓冲区域:OR为0.69,95%CI:0.51至0.93)。几乎没有证据表明步行便利性与高血压或高胆固醇血症之间存在关联。男性和女性在关联上存在差异的唯一显著证据是,男性在800米缓冲区域与2型糖尿病的关联更强。在进一步调整身体活动和久坐行为后,与肥胖和糖尿病的关联减弱,但在800米缓冲区域与肥胖的总体关联仍然显著(800米缓冲区域:OR为0.78,95%CI:0.64至0.96)。
观察到邻里步行便利性与肥胖之间存在保护性关联。邻里步行便利性可能对2型糖尿病也有保护作用,尤其是对男性。未发现与高血压或高胆固醇血症有关联。这值得进一步研究。研究结果有助于积累证据,表明旨在创造支持性环境的城市规划和政策相关策略在预防慢性病方面可能发挥重要作用。