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采用微创前路清创融合联合经Wiltse入路后路固定治疗单节段腰椎化脓性脊柱炎。

Single-level lumbar pyogenic spondylodiscitis treated with minimally invasive anterior debridement and fusion combined with posterior fixation via Wiltse approach.

作者信息

Lin Yang, Chen Wen-Jian, Zhu Wen-Tao, Li Feng, Fang Huang, Chen An-Min, Xiong Wei

机构信息

Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

J Huazhong Univ Sci Technolog Med Sci. 2013 Oct;33(5):707-712. doi: 10.1007/s11596-013-1184-x. Epub 2013 Oct 20.

Abstract

The effect and safety of anterior debridement and fusion with a minimally invasive approach combined with posterior fixation via the Wiltse approach were assessed in the single-level lumbar pyogenic spondylodiscitis. Seventeen patients from 2007 to 2009 underwent anterior debridement and fusion with a minimally invasive approach combined with posterior fixation via the Wiltse approach. Postoperative follow-up time was 24-41 months. Data included the patients' general information, microbiology, operative time, intraoperative blood loss, postoperative complications, intervertebral fusion rate, and preoperative and final follow-up scores for American Spinal Injury Association (ASIA) impairment, visual analogue scale (VAS), and Oswestry Disability Index (ODI). Ten patients had undergone a prior spinal invasive procedure, and 7 had hematogenous infection. The infected segments included L1-2, L2-3, L3-4, and L4-5 in 1, 2, 5, and 9 cases, respectively. Thirteen bacterial cultures were positive for Staphylococcus aureus (5 cases), Staphylococcus epidermidis (4), Streptococcus (3), and Escherichia coli (1). The operative time was 213.8±45.6 min, and the intraoperative blood loss was 180.6±88.1 mL. Postoperative complications consisted of urinary retention (2 cases), constipation (3), and deep vein thrombosis (2). On the final follow-up, VAS scores and ODIs were significantly lower than those of preoperation, while the ASIA grades improved. All the cases achieved good intervertebral bony fusion. Anterior debridement and fusion with a minimally invasive approach combined with posterior fixation via the Wiltse approach can successfully treat single-level lumbar pyogenic spondylodiscitis, with less trauma and reliable immobilization. It is a viable option for clinical application.

摘要

在单节段腰椎化脓性脊椎间盘炎中评估了经微创前路清创融合联合经Wiltse入路后路固定的效果及安全性。2007年至2009年期间,17例患者接受了经微创前路清创融合联合经Wiltse入路后路固定。术后随访时间为24 - 41个月。数据包括患者的一般信息、微生物学、手术时间、术中出血量、术后并发症、椎间融合率以及美国脊髓损伤协会(ASIA)损伤分级、视觉模拟评分(VAS)和Oswestry功能障碍指数(ODI)的术前及末次随访评分。10例患者曾接受过脊柱侵入性手术,7例为血源性感染。感染节段分别为L1 - 2节段1例、L2 - 3节段2例、L3 - 4节段5例和L4 - 5节段9例。13次细菌培养中,金黄色葡萄球菌阳性5例、表皮葡萄球菌阳性4例、链球菌阳性3例、大肠杆菌阳性1例。手术时间为213.8±45.6分钟,术中出血量为180.6±88.1毫升。术后并发症包括尿潴留(2例)、便秘(3例)和深静脉血栓形成(2例)。在末次随访时,VAS评分和ODI均显著低于术前,而ASIA分级有所改善。所有病例均实现了良好的椎间骨性融合。经微创前路清创融合联合经Wiltse入路后路固定可成功治疗单节段腰椎化脓性脊椎间盘炎,创伤较小且固定可靠。这是一种可行的临床应用选择。

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