基于若丹明的水溶液中 Fe3+ 的“开启”型荧光探针。
A rhodamine-based "turn-on" fluorescent probe for Fe3+ in aqueous solution.
机构信息
Department of Chemistry, Anhui University, Hefei 230601, P. R. China.
出版信息
Dalton Trans. 2014 Jan 28;43(4):1583-8. doi: 10.1039/c3dt52422a.
A water-soluble "turn-on" fluorescent probe (RD1) for Fe(3+) based on rhodamine B was designed and synthesized. The fluorescent probe showed "turn-on" fluorescent and colorimetric responses to Fe(3+) with a high selectivity in water containing less than 1% organic cosolvent. Furthermore, bioimaging investigations indicated that the new probe was cell permeable and suitable for monitoring intracellular Fe(3+) in living cells by confocal microscopy with low cytotoxicity.
一种基于罗丹明 B 的水溶性“开启”型荧光探针（RD1）被设计和合成。该荧光探针对 Fe(3+)表现出“开启”型荧光和比色响应，在含有小于 1%有机溶剂的水中具有高选择性。此外，生物成像研究表明，该新探针具有细胞通透性，适合通过共聚焦显微镜在活细胞中监测细胞内 Fe(3+)，且细胞毒性低。
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