关注肠道：饮食对生殖系干细胞和生育能力的影响。
Mind the gut: Dietary impact on germline stem cells and fertility.
作者信息
Gracida Xicotencatl, Eckmann Christian R
机构信息
Max Planck Institute of Molecular Cell Biology and Genetics; Dresden, Germany ; Current affiliation: FAS Center for Systems Biology; Harvard University; Cambridge, MA USA.
Max Planck Institute of Molecular Cell Biology and Genetics; Dresden, Germany.
出版信息
Commun Integr Biol. 2013 Nov 1;6(6):e26004. doi: 10.4161/cib.26004. Epub 2013 Aug 6.
Animals thrive in environments where food resources are abundant. While this correlation between population growth and food abundance is well established, much less is known about the influence of diet quality on physiological and developmental programs that support animal reproduction. Here we discuss dietary impact on fertility, and highlight a recent report on the activity of a nuclear receptor that protects against dietary metabolites to maintain germline stem cell integrity and reproduction.
动物在食物资源丰富的环境中茁壮成长。虽然种群增长与食物丰富之间的这种关联已得到充分证实，但关于饮食质量对支持动物繁殖的生理和发育程序的影响却知之甚少。在这里，我们讨论饮食对生育能力的影响，并重点介绍一份关于一种核受体活性的最新报告，该核受体可抵御饮食代谢产物以维持生殖系干细胞的完整性和繁殖能力。
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