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Ibrutinib antagonizes rituximab-dependent NK cell-mediated cytotoxicity.

作者信息

Kohrt Holbrook E, Sagiv-Barfi Idit, Rafiq Sarwish, Herman Sarah E M, Butchar Jonathon P, Cheney Carolyn, Zhang Xiaoli, Buggy Joseph J, Muthusamy Natarajan, Levy Ronald, Johnson Amy J, Byrd John C

机构信息

Division of Oncology, Department of Medicine, Stanford University Cancer Institute, Stanford, CA.

出版信息

Blood. 2014 Mar 20;123(12):1957-60. doi: 10.1182/blood-2014-01-547869.

Abstract
摘要

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本文引用的文献

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Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes.
Blood. 2013 Oct 10;122(15):2539-49. doi: 10.1182/blood-2013-06-507947. Epub 2013 Jul 25.
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N Engl J Med. 2013 Aug 8;369(6):507-16. doi: 10.1056/NEJMoa1306220. Epub 2013 Jun 19.
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CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies.
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