DMINDA：一个用于 DNA 基序识别和分析的集成网络服务器。
DMINDA: an integrated web server for DNA motif identification and analyses.
机构信息
Computational Systems Biology Laboratory, Department of Biochemistry and Molecular Biology, and Institute of Bioinformatics, University of Georgia, Athens GA 30602, USA BioEnergy Science Center (BESC), Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.
Computational Systems Biology Laboratory, Department of Biochemistry and Molecular Biology, and Institute of Bioinformatics, University of Georgia, Athens GA 30602, USA College of Computer Science and Technology, Jilin University, Changchun, China.
出版信息
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W12-9. doi: 10.1093/nar/gku315. Epub 2014 Apr 21.
DMINDA (DNA motif identification and analyses) is an integrated web server for DNA motif identification and analyses, which is accessible at http://csbl.bmb.uga.edu/DMINDA/. This web site is freely available to all users and there is no login requirement. This server provides a suite of cis-regulatory motif analysis functions on DNA sequences, which are important to elucidation of the mechanisms of transcriptional regulation: (i) de novo motif finding for a given set of promoter sequences along with statistical scores for the predicted motifs derived based on information extracted from a control set, (ii) scanning motif instances of a query motif in provided genomic sequences, (iii) motif comparison and clustering of identified motifs, and (iv) co-occurrence analyses of query motifs in given promoter sequences. The server is powered by a backend computer cluster with over 150 computing nodes, and is particularly useful for motif prediction and analyses in prokaryotic genomes. We believe that DMINDA, as a new and comprehensive web server for cis-regulatory motif finding and analyses, will benefit the genomic research community in general and prokaryotic genome researchers in particular.
DMINDA（DNA 基序识别和分析）是一个集成的 DNA 基序识别和分析的网络服务器，可在 http://csbl.bmb.uga.edu/DMINDA/ 访问。该网站向所有用户免费开放，无需登录。该服务器为 DNA 序列上的顺式调控基序分析功能提供了一套套件，这些功能对于阐明转录调控的机制非常重要：（i）基于从对照组中提取的信息，为一组给定的启动子序列发现新的基序，以及为预测基序生成的统计分数，（ii）在提供的基因组序列中扫描查询基序的实例，（iii）对识别出的基序进行比较和聚类，以及（iv）在给定启动子序列中查询基序的共现分析。该服务器由一个拥有超过 150 个计算节点的后端计算机集群提供支持，特别适用于原核基因组中的基序预测和分析。我们相信，DMINDA 作为一个新的、全面的顺式调控基序发现和分析的网络服务器，将使一般的基因组研究社区，特别是原核基因组研究人员受益。
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