聚乙二醇与小分子药物灰黄霉素之间的共晶形成。
Co-crystal formation between poly(ethylene glycol) and a small molecular drug griseofulvin.
作者信息
Zhong Zhi, Guo Canxiong, Chen Long, Xu Jun, Huang Yanbin
机构信息
Key Laboratory of Advanced Materials (MOE), Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.
出版信息
Chem Commun (Camb). 2014 Jun 18;50(48):6375-8. doi: 10.1039/c4cc00159a.
PMID:24803004
Abstract
Most of the pharmaceutical co-crystals are formed between drug molecules and small molecular compounds. Here, we demonstrated that a small molecular drug griseofulvin and poly(ethylene glycol) can also form co-crystals.
摘要
大多数药物共晶体是在药物分子和小分子化合物之间形成的。在此，我们证明了小分子药物灰黄霉素和聚乙二醇也能形成共晶体。
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