缺血性胎盘疾病的病理生理学。
Pathophysiology of ischemic placental disease.
机构信息
Magee-Womens Research Institute, Pittsburgh, PA 15213; Department of Obstetrics, Gynecology and Reproductive Sciences, Epidemiology and Clinical and Translational Research, University of Pittsburgh, Pittsburgh, PA.
出版信息
Semin Perinatol. 2014 Apr;38(3):139-45. doi: 10.1053/j.semperi.2014.03.005.
Abstract
The pregnancy disorders associated with placental ischemia share many similar pathological and pathophysiological features and are associated with the failure to deliver adequate nutrients and oxygen to the placenta. The origins of this deficiency are a subject of intense study. In this article, I review the genesis and consequences of this pathology addressing the similarities and the differences with the different disorders and addressing current gaps in our knowledge.
摘要
与胎盘缺血相关的妊娠疾病具有许多相似的病理和病理生理特征，并且与未能向胎盘输送足够的营养和氧气有关。这种缺陷的起源是一个深入研究的课题。在本文中，我回顾了这种病理学的起源和后果，探讨了不同疾病之间的相似性和差异，并讨论了我们知识中的现有空白。
相似文献
1
Pathophysiology of ischemic placental disease.
Semin Perinatol. 2014 Apr;38(3):139-45. doi: 10.1053/j.semperi.2014.03.005.
2
Ischemic placental disease: epidemiology and risk factors.
Eur J Obstet Gynecol Reprod Biol. 2011 Nov;159(1):77-82. doi: 10.1016/j.ejogrb.2011.07.025. Epub 2011 Aug 11.
3
Epidemiology of ischemic placental disease: a focus on preterm gestations.
Semin Perinatol. 2014 Apr;38(3):133-8. doi: 10.1053/j.semperi.2014.03.004.
4
Prediction and prevention of ischemic placental disease.
Semin Perinatol. 2014 Apr;38(3):177-82. doi: 10.1053/j.semperi.2014.03.002.
5
Ischemic placental disease: maternal versus fetal clinical presentations by gestational age.
J Matern Fetal Neonatal Med. 2010 Aug;23(8):887-93. doi: 10.3109/14767050903334885.
6
Long-term maternal morbidity and mortality associated with ischemic placental disease.
Semin Perinatol. 2014 Apr;38(3):146-50. doi: 10.1053/j.semperi.2014.03.003.
7
Ischemic placental disease and risks of perinatal mortality and morbidity and neurodevelopmental outcomes.
Semin Perinatol. 2014 Apr;38(3):151-8. doi: 10.1053/j.semperi.2014.03.007.
8
Second- and third-trimester biochemical and ultrasound markers predictive of ischemic placental disease.
Semin Perinatol. 2014 Apr;38(3):167-76. doi: 10.1053/j.semperi.2014.03.008.
9
Ischemic placental disease: a unifying concept for preeclampsia, intrauterine growth restriction, and placental abruption.
Semin Perinatol. 2014 Apr;38(3):131-2. doi: 10.1053/j.semperi.2014.03.001.
10
Understanding and Preventing Placenta-Mediated Pregnancy Complications.
Hamostaseologie. 2020 Aug;40(3):356-363. doi: 10.1055/a-1184-8388. Epub 2020 Jul 29.
引用本文的文献
1
The role of heat shock proteins in placental ischemic disease: A narrative review of the current literature.
Int J Gynaecol Obstet. 2025 Jun;169(3):960-967. doi: 10.1002/ijgo.70039. Epub 2025 Mar 3.
2
Arsenic and the placenta: A review with emphasis on the immune system.
Placenta. 2025 Feb;160:73-81. doi: 10.1016/j.placenta.2024.12.019. Epub 2024 Dec 24.
3
A multi-platform assessment of extracellular vesicles from the plasma and urine of women with preeclampsia.
Placenta. 2025 Jun 13;166:96-102. doi: 10.1016/j.placenta.2024.12.014. Epub 2024 Dec 28.
4
Advancing diagnosis and early risk assessment of preeclampsia through noninvasive cell-free DNA methylation profiling.
Clin Epigenetics. 2024 Dec 18;16(1):182. doi: 10.1186/s13148-024-01798-5.
5
Overexpression of long noncoding RNA DUXAP8 inhibits ER-phagy through activating AKT/mTOR signaling and contributes to preeclampsia.
Cell Mol Life Sci. 2024 Aug 9;81(1):336. doi: 10.1007/s00018-024-05385-y.
6
Ceramides during Pregnancy and Obstetrical Adverse Outcomes.
Metabolites. 2023 Nov 8;13(11):1136. doi: 10.3390/metabo13111136.
7
Pregnancy by Oocyte Donation: Reviewing Fetal-Maternal Risks and Complications.
Int J Mol Sci. 2023 Sep 11;24(18):13945. doi: 10.3390/ijms241813945.
8
Understanding PPARγ and Its Agonists on Trophoblast Differentiation and Invasion: Potential Therapeutic Targets for Gestational Diabetes Mellitus and Preeclampsia.
Nutrients. 2023 May 25;15(11):2459. doi: 10.3390/nu15112459.
9
Phytochemicals in the treatment of inflammation-associated diseases: the journey from preclinical trials to clinical practice.
Front Pharmacol. 2023 May 9;14:1177050. doi: 10.3389/fphar.2023.1177050. eCollection 2023.
10
Impact of Co-Occurrence of Obesity and SARS-CoV-2 Infection during Pregnancy on Placental Pathologies and Adverse Birth Outcomes: A Systematic Review and Narrative Synthesis.
Pathogens. 2023 Mar 27;12(4):524. doi: 10.3390/pathogens12040524.
本文引用的文献
1
Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation.
J Clin Invest. 2013 Oct;123(10):4264-72. doi: 10.1172/JCI68991. Epub 2013 Sep 16.
2
Variation in endoglin pathway genes is associated with preeclampsia: a case-control candidate gene association study.
BMC Pregnancy Childbirth. 2013 Apr 1;13:82. doi: 10.1186/1471-2393-13-82.
3
The placenta in preeclampsia.
Pregnancy Hypertens. 2012 Apr 1;2(2):72-83. doi: 10.1016/j.preghy.2012.01.001.
4
The impact of the unfolded protein response on human disease.
J Cell Biol. 2012 Jun 25;197(7):857-67. doi: 10.1083/jcb.201110131.
5
Low placental growth factor across pregnancy identifies a subset of women with preterm preeclampsia: type 1 versus type 2 preeclampsia?
Hypertension. 2012 Jul;60(1):239-46. doi: 10.1161/HYPERTENSIONAHA.112.191213. Epub 2012 May 29.
6
The vascular endothelial growth factor family in adverse pregnancy outcomes.
Hum Reprod Update. 2012 Jul;18(4):436-57. doi: 10.1093/humupd/dms011. Epub 2012 Apr 11.
7
Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy.
Nature. 2012 Mar 21;484(7393):246-50. doi: 10.1038/nature10897.
8
Thymic stromal lymphopoietin downregulates NME1 expression and promotes invasion in human trophoblasts via the activation of STAT3 signaling pathway.
Clin Immunol. 2012 Apr;143(1):88-95. doi: 10.1016/j.clim.2012.01.013. Epub 2012 Feb 9.
9
Effects of interleukin-6 on extravillous trophoblast invasion in early human pregnancy.
Mol Hum Reprod. 2012 Aug;18(8):391-400. doi: 10.1093/molehr/gas010. Epub 2012 Feb 22.
10
Lipopolysaccharide induces cytokine production and decreases extravillous trophoblast invasion through a mitogen-activated protein kinase-mediated pathway: possible mechanisms of first trimester placental dysfunction.
Hum Reprod. 2012 Jan;27(1):61-72. doi: 10.1093/humrep/der362. Epub 2011 Nov 3.
Zotero 插件