肝纤维化：MR 弹性成像和 US 剪切波弹性成像评估的前瞻性比较。
Hepatic fibrosis: prospective comparison of MR elastography and US shear-wave elastography for evaluation.
机构信息
From the Departments of Radiology (J.H.Y., J.M.L., I.J., E.S.L., J.Y.S., S.K.J., J.K.H., B.I.C.) and Pathology (K.B.L.), Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea; and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea (J.M.L., J.K.H., B.I.C.).
出版信息
Radiology. 2014 Dec;273(3):772-82. doi: 10.1148/radiol.14132000. Epub 2014 Jul 7.
PURPOSE
To compare magnetic resonance (MR) elastography and ultrasonographic shear-wave elastography ( SWE shear-wave elastography ) for the staging of hepatic fibrosis ( HF hepatic fibrosis ) in the same individuals.
MATERIALS AND METHODS
This prospective study was approved by the institutional review board, and informed consent was obtained from all patients. The technical success of and reliable liver stiffness ( LS liver stiffness ) measurement rates at MR elastography and SWE shear-wave elastography were compared in 129 patients who underwent both examinations. For mutual validation, LS liver stiffness values measured at both examinations were correlated by using Pearson correlation. The diagnostic performance of the two techniques for the assessment of substantial HF hepatic fibrosis (stage ≥ F2) was compared by using nonparametric receiver operating characteristic analysis.
RESULTS
The technical success rates of MR elastography and SWE shear-wave elastography were 95.35% (123 of 129) and 97.67% (126 of 129), respectively (P = .51). MR elastography provided significantly more reliable LS liver stiffness measurements than did SWE shear-wave elastography (95.35% [123 of 129] vs 75.2% [97 of 129], P < .001). The two examinations showed moderate correlation (r = 0.724). In patients with HF hepatic fibrosis stages of F3 or lower, the two examinations showed moderate-to-strong correlation (r = 0.683 in normal livers, 0.754 in livers with stage F0 or F1 HF hepatic fibrosis , and 0.90 in livers with stage F2 or F3 HF hepatic fibrosis ; P < .001); however, they did not show significant correlation for stage F4 HF hepatic fibrosis (r = 0.30, P = .31). MR elastography and SWE shear-wave elastography showed similar diagnostic capability in depicting HF hepatic fibrosis of stage F2 or greater (P = .98) when LS liver stiffness measurements were reliably performed.
CONCLUSION
MR elastography and SWE shear-wave elastography showed moderate correlation and similar diagnostic performance in the diagnosis of HF hepatic fibrosis of stage F2 or greater; however, MR elastography yielded more reliable LS liver stiffness measurements than did SWE shear-wave elastography .
目的
比较磁共振弹性成像（MR 弹性成像）和超声剪切波弹性成像（SWE 剪切波弹性成像）在同一人群中对肝纤维化（HF 肝纤维化）分期的作用。
材料与方法
本前瞻性研究经机构审查委员会批准，并获得所有患者的知情同意。比较 129 例同时接受这两种检查的患者中，MR 弹性成像和 SWE 剪切波弹性成像的技术成功率和可靠的肝硬度（LS 肝硬度）测量率。为了相互验证，通过 Pearson 相关分析比较两种检查中 LS 肝硬度值的相关性。采用非参数接收器工作特征分析比较两种技术对评估大量 HF 肝纤维化（分期≥F2）的诊断性能。
结果
MR 弹性成像和 SWE 剪切波弹性成像的技术成功率分别为 95.35%（123/129）和 97.67%（126/129）（P=.51）。MR 弹性成像提供的 LS 肝硬度测量值明显比 SWE 剪切波弹性成像更可靠（95.35%[123/129]与 75.2%[97/129]，P<.001）。两种检查方法相关性中等（r=0.724）。在 HF 肝纤维化分期为 F3 或更低的患者中，两种检查方法显示出中等至强相关性（正常肝脏 r=0.683，F0 或 F1 HF 肝纤维化 r=0.754，F2 或 F3 HF 肝纤维化 r=0.90；P<.001）；然而，对于 F4 HF 肝纤维化，它们之间没有显示出显著的相关性（r=0.30，P=.31）。当可靠地进行 LS 肝硬度测量时，MR 弹性成像和 SWE 剪切波弹性成像在描绘 HF 肝纤维化 F2 或更高阶段时具有相似的诊断能力（P=.98）。
结论
MR 弹性成像和 SWE 剪切波弹性成像在诊断 HF 肝纤维化 F2 或更高阶段时具有中等相关性和相似的诊断性能；然而，MR 弹性成像比 SWE 剪切波弹性成像产生更可靠的 LS 肝硬度测量值。
Zotero 插件