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一种用于在水性介质中检测多种分析物(Cr³⁺、Al³⁺和Fe³⁺)的单分子探针及其生物学应用。

A single molecular probe for multi-analyte (Cr³⁺, Al³⁺ and Fe³⁺) detection in aqueous medium and its biological application.

作者信息

Wang Junfeng, Li Yingbo, Patel Nikul G, Zhang Ge, Zhou Demin, Pang Yi

机构信息

Department of Chemistry, The University of Akron, Akron, Ohio 44325, USA.

出版信息

Chem Commun (Camb). 2014 Oct 21;50(82):12258-61. doi: 10.1039/c4cc04731a.

Abstract

An ESIPT based fluorescent sensor 1 was developed, which could selectively detect and differentiate trivalent metal ions Cr(3+), Al(3+) and Fe(3+) in aqueous medium. The cell imaging experiments confirmed that 1 can be used for monitoring intracellular Cr(3+) and Al(3+) levels in living cells.

摘要

开发了一种基于激发态分子内质子转移(ESIPT)的荧光传感器1,它能够在水性介质中选择性地检测和区分三价金属离子Cr(3+)、Al(3+)和Fe(3+)。细胞成像实验证实,1可用于监测活细胞内的Cr(3+)和Al(3+)水平。

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