巴西圣保罗州幼儿百日咳感染源
Sources of pertussis infection in young babies from São Paulo State, Brazil.
作者信息
Berezin Eitan Naaman, de Moraes José Cassio, Leite Daniela, Carvalhanas Telma Regina M P, Yu Ana Lucia Frugis, Blanco Roberta Morozetti, Rodrigues Marcela, Almeida Flavia J, Bricks Lucia Ferro
机构信息
From the *Pediatric Infectious Diseases; †Epidemiology Department-Faculdade de Ciencias Médicas da Santa Casa de São Paulo, School Medicine of Santa Casa de São Paulo; ‡Laboratory for Pertussis-Instituto Adolfo Lutz-State Secretary Office of Health; §Division of Respiratory Diseases, Epidemiological Vigilance Center, State Secretary Office of Health; ¶Instituto Adolfo Lutz MSci-Instituto Adolfo Lutz-State Secretary Office of Health; and ‖Sanofi Pasteur, Sao Paulo, Brazil.
出版信息
Pediatr Infect Dis J. 2014 Dec;33(12):1289-91. doi: 10.1097/INF.0000000000000424.
Household contacts are important sources of Bordetella pertussis in infants. A total of 353 household contacts of 97 index cases were evaluated for pertussis by culture and polymerase chain reaction. Twenty eight contacts were positive (8.0%). The presence of symptoms did not influence the rate of diagnosed bacteriologic pertussis in communicants. We conclude that contacts with an index case can be positive for B. pertussis independently of the presence of symptoms.
家庭接触者是婴儿百日咳博德特氏菌的重要来源。对97例索引病例的353名家庭接触者进行了培养和聚合酶链反应检测以评估百日咳情况。28名接触者呈阳性（8.0%）。症状的出现并不影响感染者中确诊的细菌性百日咳发病率。我们得出结论，与索引病例的接触者可能百日咳博德特氏菌呈阳性，而与症状的有无无关。
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