迷迭香叶作为生物活性化合物的天然来源。
Rosmarinus officinalis leaves as a natural source of bioactive compounds.
作者信息
Borrás-Linares Isabel, Stojanović Zorica, Quirantes-Piné Rosa, Arráez-Román David, Švarc-Gajić Jaroslava, Fernández-Gutiérrez Alberto, Segura-Carretero Antonio
机构信息
Department of Analytical Chemistry, University of Granada, c/Fuentenueva s/n, 18071 Granada, Spain.
Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia.
出版信息
Int J Mol Sci. 2014 Nov 10;15(11):20585-606. doi: 10.3390/ijms151120585.
In an extensive search for bioactive compounds from plant sources, the composition of different extracts of rosemary leaves collected from different geographical zones of Serbia was studied. The qualitative and quantitative characterization of 20 rosemary (Rosmarinus officinalis) samples, obtained by microwave-assisted extraction (MAE), was determined by high performance liquid chromatography coupled to electrospray quadrupole-time of flight mass spectrometry (HPLC-ESI-QTOF-MS). The high mass accuracy and true isotopic pattern in both MS and MS/MS spectra provided by the QTOF-MS analyzer enabled the characterization of a wide range of phenolic compounds in the extracts, including flavonoids, phenolic diterpenes and abietan-type triterpenoids, among others. According to the data compiled, rosemary samples from Sokobanja presented the highest levels in flavonoids and other compounds such as carnosol, rosmaridiphenol, rosmadial, rosmarinic acid, and carnosic acid. On the other hand, higher contents in triterpenes were found in the extracts of rosemary from Gložan (Vojvodina).
在广泛寻找植物源生物活性化合物的过程中，对从塞尔维亚不同地理区域采集的迷迭香叶不同提取物的成分进行了研究。通过微波辅助萃取（MAE）获得的20个迷迭香（Rosmarinus officinalis）样品的定性和定量表征，采用高效液相色谱-电喷雾四极杆飞行时间质谱联用仪（HPLC-ESI-QTOF-MS）进行测定。QTOF-MS分析仪在MS和MS/MS谱图中提供的高质量准确度和真实同位素模式，能够对提取物中的多种酚类化合物进行表征，包括黄酮类化合物、酚类二萜和枞酸型三萜等。根据汇总的数据，来自索科巴尼亚的迷迭香样品中黄酮类化合物以及其他化合物如鼠尾草酚、迷迭香二酚、迷迭香酸、迷迭香酸和鼠尾草酸的含量最高。另一方面，在来自格洛赞（伏伊伏丁那）的迷迭香提取物中发现三萜类化合物的含量较高。
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