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RCSB蛋白质数据库:基础与应用研究及教育的结构生物学视角。

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education.

作者信息

Rose Peter W, Prlić Andreas, Bi Chunxiao, Bluhm Wolfgang F, Christie Cole H, Dutta Shuchismita, Green Rachel Kramer, Goodsell David S, Westbrook John D, Woo Jesse, Young Jasmine, Zardecki Christine, Berman Helen M, Bourne Philip E, Burley Stephen K

机构信息

RCSB Protein Data Bank, San Diego Supercomputer Center, University of California San Diego, La Jolla, CA 92093, USA

RCSB Protein Data Bank, San Diego Supercomputer Center, University of California San Diego, La Jolla, CA 92093, USA.

出版信息

Nucleic Acids Res. 2015 Jan;43(Database issue):D345-56. doi: 10.1093/nar/gku1214. Epub 2014 Nov 26.

Abstract

The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and providing new structural views of biology that support both basic and applied research and education. Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web. We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations. Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f6c/4383988/5cfa78eb5231/gku1214fig1.jpg

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