Wang Tao, Sun Jun-Ying, Zha Guo-Chun, Jiang Tao, You Zhen-Jun, Yuan De-Jing
Orthopedics. 2014 Dec;37(12):e1117-23. doi: 10.3928/01477447-20141124-60.
Femoral head necrosis is a rare but devastating complication following femoral neck fracture. The reported incidence of avascular necrosis after femoral neck fracture fixation varies widely, and there is no consensus regarding its risk factors. The aim of this study was to analyze the risk factors for femoral head necrosis after internal fixation in femoral neck fracture. This retrospective study included 166 patients with femoral neck fractures treated with surgical reduction and internal fixation at the authors' institution from January 2004 to December 2008. Eight patients died for reasons unrelated to the surgery, and 12 patients were lost to follow-up. The remaining 146 patients (146 fractures) were followed until union or until conversion to total hip arthroplasty. The patients included 61 males and 85 females with an average age of 47.5 years (range, 18-68 years). The authors analyzed the following factors: age, sex, Garden classification, reduction quality, surgical methods, injury-to-surgery interval, preoperative traction, weight-bearing time, and implant removal. All patients were followed for a mean of 52 months (range, 6-90 months). The incidence of femoral head necrosis was 14.4% (21/146). Garden classification (P=.012), reduction quality (P=.008), implant removal (P=.020), and preoperative traction (P=.003) were significantly associated with femoral head necrosis. Patient age (P=.990), sex (P=.287), injury-to-surgery interval (P=.360), weight-bearing time (P=.868), and surgical methods (P=.987) were not significantly associated with femoral head necrosis. In multivariate logistic regression analysis, implant removal was not a significant risk factor for femoral head necrosis development (P=.498). Garden classification, reduction quality, and preoperative traction had a significant effect on femoral head necrosis development.
股骨头坏死是股骨颈骨折后一种罕见但极具破坏性的并发症。股骨颈骨折内固定术后报道的股骨头缺血性坏死发生率差异很大,且关于其危险因素尚无共识。本研究的目的是分析股骨颈骨折内固定术后股骨头坏死的危险因素。这项回顾性研究纳入了2004年1月至2008年12月在作者所在机构接受手术复位及内固定治疗的166例股骨颈骨折患者。8例患者因与手术无关的原因死亡,12例患者失访。其余146例患者(146处骨折)随访至骨折愈合或转为全髋关节置换术。患者包括61例男性和85例女性,平均年龄47.5岁(范围18 - 68岁)。作者分析了以下因素:年龄、性别、Garden分型、复位质量、手术方法、受伤至手术间隔时间、术前牵引、负重时间及内固定取出情况。所有患者平均随访52个月(范围6 - 90个月)。股骨头坏死发生率为14.4%(21/146)。Garden分型(P = 0.012)、复位质量(P = 0.008)、内固定取出(P = 0.020)及术前牵引(P = 0.003)与股骨头坏死显著相关。患者年龄(P = 0.990)、性别(P = 0.287)、受伤至手术间隔时间(P = 0.360)、负重时间(P = 0.868)及手术方法(P = 0.987)与股骨头坏死无显著相关性。在多因素logistic回归分析中,内固定取出不是股骨头坏死发生的显著危险因素(P = 0.498)。Garden分型、复位质量及术前牵引对股骨头坏死的发生有显著影响。