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接触预防措施对住院患者跌倒、压疮以及耐甲氧西林金黄色葡萄球菌(MRSA)和耐万古霉素肠球菌(VRE)传播的影响。

Impact of contact precautions on falls, pressure ulcers and transmission of MRSA and VRE in hospitalized patients.

作者信息

Gandra S, Barysauskas C M, Mack D A, Barton B, Finberg R, Ellison R T

机构信息

Center for Disease Dynamics, Economics and Policy, 1616 P Street NW, Suite 430, Washington, DC 20036, USA.

出版信息

J Hosp Infect. 2014 Nov;88(3):170-6. doi: 10.1016/j.jhin.2014.09.003.

Abstract

BACKGROUND

Hospitals use contact precautions to prevent the spread of meticillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). There is concern that contact precautions may have adverse effects on the safety of isolated patients. In November 2010, the infection control policy at an academic medical centre was modified, and contact precautions were discontinued for patients colonized or infected with MRSA or VRE (MRSA/VRE patients).

AIM

To assess the rates of falls and pressure ulcers among MRSA/VRE patients and other adult medical-surgical patients, as well as changes in MRSA and VRE transmission before and after the policy change.

METHODS

A single-centre retrospective hospital-wide cohort study was performed from 1st November 2009 to 31st October 2011.

FINDINGS

Rates of falls and pressure ulcers were significantly higher among MRSA/VRE patients compared with other adult medical-surgical patients before the policy change (falls: 4.57 vs 2.04 per 1000 patient-days, P < 0.0001; pressure ulcers: 4.87 vs 1.22 per 1000 patient-days, P < 0.0001) and after the policy change (falls: 4.82 vs 2.10 per 1000 patient-days, P < 0.0001; pressure ulcers: 4.17 vs 1.19 per 1000 patient-days, P < 0.0001). No significant differences in the rates of falls and pressure ulcers among MRSA/VRE patients were found after the policy change compared with before the policy change. There was no overall change in MRSA or VRE hospital-acquired transmission.

CONCLUSION

MRSA/VRE patients had higher rates of falls and pressure ulcers compared with other adult medical-surgical patients. Rates were not affected by removal of contact precautions, suggesting that other factors contribute to these complications. Further research is required among this population to prevent complications.

摘要

背景

医院采用接触预防措施以防止耐甲氧西林金黄色葡萄球菌(MRSA)和耐万古霉素肠球菌(VRE)的传播。有人担心接触预防措施可能会对隔离患者的安全产生不利影响。2010年11月,一家学术医疗中心修改了感染控制政策,对于定植或感染MRSA或VRE的患者(MRSA/VRE患者)不再采取接触预防措施。

目的

评估MRSA/VRE患者及其他成年内科-外科患者的跌倒率和压疮发生率,以及政策变更前后MRSA和VRE传播情况的变化。

方法

于2009年11月1日至2011年10月31日在一家单中心进行了一项全院范围的回顾性队列研究。

研究结果

在政策变更前,MRSA/VRE患者的跌倒率和压疮发生率显著高于其他成年内科-外科患者(跌倒率:每1000患者日分别为4.57例和2.04例,P<0.0001;压疮发生率:每1000患者日分别为4.87例和1.22例,P<0.0001),在政策变更后亦是如此(跌倒率:每1000患者日分别为4.82例和2.10例,P<0.0001;压疮发生率:每1000患者日分别为4.17例和1.19例,P<0.0001)。与政策变更前相比,政策变更后MRSA/VRE患者的跌倒率和压疮发生率无显著差异。MRSA或VRE医院获得性传播没有总体变化。

结论

与其他成年内科-外科患者相比,MRSA/VRE患者的跌倒率和压疮发生率更高。去除接触预防措施并未影响发生率,这表明其他因素导致了这些并发症。需要对这一人群进行进一步研究以预防并发症。

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